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T8656

Sigma-Aldrich

Thiourea

ACS reagent, ≥99.0%

Synonym(s):
Sulfourea, Thiocarbamide
Linear Formula:
NH2CSNH2
CAS Number:
Molecular Weight:
76.12
Beilstein:
605327
EC Number:
MDL number:
PubChem Substance ID:

grade

ACS reagent

Quality Level

Assay

≥99.0%

ign. residue

≤0.1% (as SO4)

loss

≤0.5% loss on drying, 105°C, 2h

mp

170-176 °C (lit.)
174-177 °C

solubility

H2O: passes test

SMILES string

NC(N)=S

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

InChI key

UMGDCJDMYOKAJW-UHFFFAOYSA-N

Gene Information

mouse ... Ephx2(13850)

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T7875PHR175830885
Thiourea ACS reagent, ≥99.0%

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T8656

Thiourea

Thiourea ReagentPlus®, ≥99.0%

Sigma-Aldrich

T7875

Thiourea

Thiourea Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1758

Thiourea

Thiourea ≥99.999% (metals basis)

Supelco

30885

Thiourea

assay

≥99.0%

assay

≥99.0%

assay

-

assay

≥99.999% (metals basis)

mp

170-176 °C (lit.), 174-177 °C

mp

170-176 °C (lit.)

mp

170-176 °C (lit.)

mp

170-176 °C (lit.)

solubility

H2O: passes test

solubility

-

solubility

-

solubility

-

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

100

grade

ACS reagent

grade

-

grade

certified reference material, pharmaceutical secondary standard

grade

-

ign. residue

≤0.1% (as SO4)

ign. residue

-

ign. residue

-

ign. residue

-

General description

Thiourea is an analogue of urea containing sulphur.

Application

Thiourea has been used:
  • as a component of lysis buffer for liver tissue homogenization
  • in 2-D sample buffer for two-dimensional in-gel protein tyrosine phosphatases (PTP) assay
  • in rehydration buffer for protein extraction

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins

Biochem/physiol Actions

Thiourea is a free radical scavenger of the peroxide radical. It was shown to inhibit lipid peroxidation and ultraviolet (UV)-induced crosslinking of collagen. Bud dormancy in plants can be inhibited by thiourea which is used as a growth stimulator. It is also known to be used in the treatment of hyperthyroidism.

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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