All Photos(1)

T176

Supelco

4-Hydroxytamoxifen

analytical standard, (E) and (Z) isomers (50:50)

Synonym(s):
4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol, cis/trans-4-Hydroxytamoxifen, 4-OHT
Empirical Formula (Hill Notation):
C26H29NO2
CAS Number:
Molecular Weight:
387.51
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

analytical standard

form

powder

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

solubility

ethanol: 20 mg/mL

antibiotic activity spectrum

neoplastics

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Mode of action

enzyme | inhibits

SMILES string

CC\C(c1ccccc1)=C(/c2ccc(O)cc2)c3ccc(OCCN(C)C)cc3.CC\C(c4ccccc4)=C(\c5ccc(O)cc5)c6ccc(OCCN(C)C)cc6

InChI

1S/2C26H29NO2/c2*1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h2*5-17,28H,4,18-19H2,1-3H3/b26-25+;26-25-

InChI key

ZJLDABGSDWXVGE-BDSXMVAQSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

10, 50 mg in poly bottle

Biochem/physiol Actions

Metabolite of the chemotherapeutic drug tamoxifen, exhibiting more potent estrogen agonist/antagonist activity than the parent drug. Also active as intra-membranous inhibitor of lipid peroxidation.

Pictograms

Exclamation markHealth hazard

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Certificate of Origin

More documents

Quotes and Ordering

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Clustering of strong replicators associated with active promoters is sufficient to establish an early-replicating domain.
Brossas, et al.
The Embo Journal, 39, e99520-e99520 (2021)
Olga S Koutsopoulos et al.
PloS one, 6(11), e27498-e27498 (2011-11-19)
The large GTPase dynamin 2 is a key player in membrane and cytoskeletal dynamics mutated in centronuclear myopathy (CNM) and Charcot-Marie Tooth (CMT) neuropathy, two discrete dominant neuromuscular disorders affecting skeletal muscle and peripheral nerves respectively. The molecular basis for
Paolo Cinelli et al.
BMC developmental biology, 8, 57-57 (2008-05-27)
The transcription factor STAT3 is a downstream target of the LIF signalling cascade. LIF signalling or activation is sufficient to maintain embryonic stem (ES) cells in an undifferentiated and pluripotent state. To further investigate the importance of STAT3 in the

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