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S1000000

Sorbitol

European Pharmacopoeia (EP) Reference Standard

Synonym(s):
D-Sorbitol, D-Glucitol
Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
Molecular Weight:
182.17
Beilstein:
1721899
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

vapor density

<1 (vs air)

vapor pressure

<0.1 mmHg ( 25 °C)

API family

sorbitol

manufacturer/tradename

EDQM

mp

98-100 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-JGWLITMVSA-N

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1 of 4

This Item
1617000PHR10061.02975
Sorbitol European Pharmacopoeia (EP) Reference Standard

S1000000

Sorbitol

Sorbitol United States Pharmacopeia (USP) Reference Standard

USP

1617000

Sorbitol

Sorbitol Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1006

Sorbitol

Sorbitol FP, liquid, (sorbitol syrup, noncrystallizing), EMPROVE&#174; ESSENTIAL, Ph. Eur., BP, NF, E 420

SAFC

1.02975

Sorbitol

manufacturer/tradename

EDQM

manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

application(s)

liquid formulation
pharmaceutical

format

neat

format

neat

format

neat

format

-

vapor density

<1 (vs air)

vapor density

<1 (vs air)

vapor density

<1 (vs air)

vapor density

<1 (vs air)

vapor pressure

<0.1 mmHg ( 25 °C)

vapor pressure

<0.1 mmHg ( 25 °C)

vapor pressure

<0.1 mmHg ( 25 °C)

vapor pressure

<0.1 mmHg ( 25 °C)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the Issuing Pharmacopoeia.

For further information and support please go to the website of the issuing Pharmacopoeia.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia. Their suitability for any other use is not guaranteed and is the sole responsibility of the user. This standard is not intended for human or animal use.
Established for the preparation of the below-given solutions as per European Pharmacopoeia:
  • Reference solutions (a) and (b) in the identification by thin-layer chromatography (General text 2.2.27) and testing for related substances and assay using liquid chromatography (General text 2.2.29) of sorbitol, according to the monograph 0435
  • Reference solutions (a) in the assay of sorbitol liquid (crystallizing), sorbitol liquid (non-crystallizing), and sorbitol, liquid, partially dehydrated using liquid chromatography (General text 2.2.29), according to the monographs 0436, 0437, and 2048 respectively
  • Reference solutions (b) in the identification and assay of maltitol, liquid using thin-layer chromatography (General text 2.2.27), and liquid chromatography (General text 2.2.29), according to the monograph 1236

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Caution

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Sorbitol

Sorbitol
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3865-3867 (2019)
Anna Boccaccio et al.
Cellular and molecular life sciences : CMLS, 71(21), 4275-4283 (2014-04-29)
Two-pore channel proteins (TPC) encode intracellular ion channels in both animals and plants. In mammalian cells, the two isoforms (TPC1 and TPC2) localize to the endo-lysosomal compartment, whereas the plant TPC1 protein is targeted to the membrane surrounding the large
Youngkook Kwon et al.
ChemSusChem, 6(3), 455-462 (2013-01-25)
This Full Paper addresses the electrocatalytic hydrogenation of glucose to sorbitol or 2-deoxysorbitol on solid metal electrodes in neutral media. Combining voltammetry and online product analysis with high-performance liquid chromatography (HPLC), provides both qualitative and quantitative information regarding the reaction
Rajesh Chandramohanadas et al.
The Journal of infectious diseases, 210(10), 1616-1626 (2014-05-28)
Malaria causes nearly 1 million deaths annually. Recent emergence of multidrug resistance highlights the need to develop novel therapeutic interventions against human malaria. Given the involvement of sugar binding plasmodial proteins in host invasion, we set out to identify such
J M van Griensven et al.
Clinical pharmacology and therapeutics, 58(6), 631-640 (1995-12-01)
To examine the effect of diabetes mellitus on the pharmacokinetics of tolrestat and to investigate its effect on red blood cell sorbitol levels according to a new pharmacodynamic model for this class of drugs. Single and multiple doses of tolrestat

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