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PHR1006

Supelco

Sorbitol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
D-Glucitol, D-Sorbitol
Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
Molecular Weight:
182.17
Beilstein:
1721899
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

certified reference material
pharmaceutical secondary standard

Agency

traceable to Ph. Eur. S100000
traceable to USP 1617000

vapor density

<1 (vs air)

vapor pressure

<0.1 mmHg ( 25 °C)

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

98-100 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-JGWLITMVSA-N

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General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Sorbitol may be used as an internal standard in the quantitative determination ofD-glucose in corn sugar and corn syrups using gas liquid chromatography (GLC).
Sorbitol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography technique.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB7795 in the slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

More Documents

Quotes and Ordering

An isocratic HPLC method for the determination of sorbitol and glycerol in pharmaceutical formulations
Simonzadeh N and Ronsen B
Journal of Chromatographic Science, 50(7), 644-647 (2012)
Determination of nimesulide in pharmaceutical dosage forms by second order derivative UV spectrophotometry
Altinoz S and Dursun OO
Journal of Pharmaceutical and Biomedical Analysis, 22(1), 175-182 (2000)
Use of sorbitol as internal standard in determination of D-glucose by gas liquid chromatography
Alexander.J.R and Garbutt.T.J
Analytical Chemistry, 37, 303-305 (1965)
Arlene E Dent et al.
PloS one, 3(10), e3557-e3557 (2008-10-30)
Antibodies that impair Plasmodium falciparum merozoite invasion and intraerythrocytic development are one of several mechanisms that mediate naturally acquired immunity to malaria. Attempts to correlate anti-malaria antibodies with risk of infection and morbidity have yielded inconsistent results. Growth inhibition assays
Youngkook Kwon et al.
ChemSusChem, 6(3), 455-462 (2013-01-25)
This Full Paper addresses the electrocatalytic hydrogenation of glucose to sorbitol or 2-deoxysorbitol on solid metal electrodes in neutral media. Combining voltammetry and online product analysis with high-performance liquid chromatography (HPLC), provides both qualitative and quantitative information regarding the reaction

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