PHR1551

Supelco

Acetonitrile

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
Cyanomethane, Methyl cyanide, Acetonitrile, ACN, Ethyl nitrile
Linear Formula:
CH3CN
CAS Number:
Molecular Weight:
41.05
Beilstein/REAXYS Number:
741857
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

certified reference material
pharmaceutical secondary standard

vapor density

1.41 (vs air)

vapor pressure

72.8 mmHg ( 20 °C)

CofA

current certificate can be downloaded

autoignition temp.

973 °F

expl. lim.

16 %

packaging

ampule of 3x1.2 mL each

application(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.344 (lit.)

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

density

0.786 g/mL at 25 °C (lit.)

Featured Industry

Pharmaceutical (small molecule)

format

neat

pharmacopeia traceability

traceable to USP 1601340

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Acetonitrile is an aliphatic nitrile, widely used as a solvent and intermediate in organic syntheses. It is also used in cosmetic products, and as a chemical intermediate in the manufacturing of pesticides and in industrial extraction process.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB7855 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictograms

FlameExclamation mark

Signal Word

Danger

hazcat

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

storage_class_code

3 - Flammable liquids

WGK Germany

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2.0 °C - closed cup

Certificate of Analysis

Certificate of Origin

Toxicology Desk Reference: The Toxic Exposure & Medical Monitoring Index (2019)
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Protocols
GC Analysis of Class 2 Residual Solvents on OVI-G43
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