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D8787

Sigma-Aldrich

Dextran sulfate sodium salt from Leuconostoc spp.

avg mol wt >500,000 (dextran starting material)

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About This Item

CAS Number:
9011-18-1
MDL number:
MFCD00081551
UNSPSC Code:
12352201
NACRES:
NA.21

biological source

bacterial (Leuconostoc)

Quality Level

200

form

powder or crystals

mol wt

avg mol wt >500,000 (dextran starting material)

composition

Sulfur Content, 16.0-19.0% (dry basis)

color

white to off-white

pH

6.0-8.0

solubility

H2O: 100 mg/mL

Application


  • Determining the protective effects of Ma-Mu-Ran Antidiarrheal Capsules against acute DSS-induced enteritis using 16S rRNA gene sequencing and fecal metabolomics.: This study explores the protective effects of Ma-Mu-Ran on acute enteritis, highlighting the role of microbial interactions facilitated by dextran sulfate sodium salt, potentially beneficial for biochemists focusing on gut microbiome dynamics (Zheng et al., 2022).

  • Immunomodulatory and anti-inflammatory properties of artesunate in experimental colitis.: Examines the immunomodulatory effects of artesunate, potentially enhanced by adjuvants such as dextran sulfate sodium salt, pertinent to biochemists studying inflammation and immune responses (Yang et al., 2012).

  • Enantiomeric separation of drugs by affinity electrokinetic chromatography using dextran sulfate.: Investigates the application of dextran sulfate sodium salt in the chiral separation of pharmaceuticals, offering a technique of interest for biochemical analysis and drug development (Nishi et al., 1994).

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCD7532
BCBW4585
BCBS3124V
BCBS3124
MKBT0742V

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Siroon Bekkering et al.
Clinical science (London, England : 1979), 133(10), 1185-1196 (2019-05-16)
Atherosclerosis is a chronic inflammatory disease that has its origins in early life. Postnatal inflammation exacerbates atherosclerosis, but the possible effect of intrauterine inflammation is largely unexplored. Exposure to inflammation in utero is common, especially in infants born preterm, who
Aaron H Rose et al.
Inflammatory bowel diseases, 21(9), 2005-2015 (2015-06-16)
An important role has emerged for calpain enzymes in regulating inflammation with one isoform, calpain-2, particularly important for macrophage activation. The goal of this study was to determine the therapeutic potential of a synthetic calpain-2 inhibitor, zLLY-CH2F, for colitis and

Protocols

Dextran Sulfate

Dextran sulfates are supplied as the sodium salt forms, making them soluble and stable in water. Dextran sulfate contains approximately 17% sulfur which is equivalent to approximately 2.3 sulfate groups per glucosyl residue.

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