D1685

Sigma-Aldrich

Docusate sodium

meets USP testing specifications

Synonym(s):
Docusate sodium salt, Sulfosuccinic acid bis(2-ethylhexyl) ester sodium salt, AOT, Sodium bis(2-ethylhexyl) sulfosuccinate, Sulfobutanedioic acid bis(2-ethylhexyl ester) sodium salt, ‘Dioctyl’ sulfosuccinate sodium salt, Bis(2-ethylhexyl) sulfosuccinate sodium salt
Empirical Formula (Hill Notation):
C20H37NaO7S
CAS Number:
Molecular Weight:
444.56
Beilstein/REAXYS Number:
4117588
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

Agency/Method

meets USP testing specifications

description

anionic

assay

99.0-100.5% anhydrous basis

mol wt

444.56 g/mol

application(s)

detection: suitable
protein quantification: suitable

Featured Industry

Pharmaceutical (small molecule)

SMILES string

[Na+].CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S([O-])(=O)=O

InChI

1S/C20H38O7S.Na/c1-5-9-11-16(7-3)14-26-19(21)13-18(28(23,24)25)20(22)27-15-17(8-4)12-10-6-2;/h16-18H,5-15H2,1-4H3,(H,23,24,25);/q;+1/p-1

InChI key

APSBXTVYXVQYAB-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Docusate sodium (sodium dioctylsulfosuccinate, DOSS) is commonly used as a surfactant, food additive and stool softener.

Application

Docusate sodium (DOSS, AOT) has been used in the preparation of the following:
  • Luminescent ceramics (phosphors).
  • Stock solution during the quantification of DOSS in sea food by using liquid chromatography tandem mass spectrometry (LC-MS/MS).
  • AOT-water-isooctane reverse micelle system
It has also been used in a study to understand its effect on protein bioactivity, when it is co-encapsulates with proteins in polymer based microsphere systems.
Forms reverse micelles in hydrocarbon solvents; Suitable for the solubilization of the major myelin transmembrane proteolipid

Packaging

100, 500 g in poly bottle

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

hazcat

Eye Dam. 1 - Skin Irrit. 2

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 2

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Determination of dioctylsulfosuccinate in select seafoods using a QuEChERS extraction with liquid chromatography-triple quadrupole mass spectrometry.
Boyd BL, et al.
Laboratory Information Bulletin (2010)
Preparation and characterization of rare-earth-doped Y2O3 luminescent ceramics by the use of reverse micelles.
Graeve OA and Corral JO.
Opt. Mater., 29(1), 24-30 (2006)
Protein bioactivity and polymer orientation is affected by stabilizer incorporation for double-walled microspheres.
Kokai LE, et al.
J. Controlled Release, 141(2), 168-176 (2010)
Johnson Mathew et al.
Journal of chromatography. A, 1231, 46-51 (2012-03-01)
Dioctyl sulfosuccinate (DOSS) was a major component of the dispersants most used in the 2010 Deepwater Horizon Oil Spill incident response. This analytical method quantifies salt water DOSS concentrations to a reporting limit of 20 μg/L, which was below the...
Sonali V Kapse et al.
International journal of pharmaceutics, 429(1-2), 104-112 (2012-03-15)
We disclose a self nanoprecipitating preconcentrate (SNP) of tamoxifen citrate (TMX), which forms TMX loaded polymeric nanoparticles, on dilution with aqueous media. SNP comprised TMX, polymer (Kollidon SR) and surfactant/s dissolved in a pharmaceutically acceptable vehicle. Binary surfactant mixtures of...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service