82270

1,2-Dichloropropane

99%

• Synonym(s): Propylene dichloride
• Linear Formula: CH₃CHClCH₂Cl
• CAS Number: 78-87-5
• Molecular Weight: 112.99
• Beilstein/REAXYS Number: 1718880
• EC Number: 201-152-2
• MDL number: MFCD00000868
• UNSPSC Code: 12352100
• PubChem Substance ID: 329769241
• NACRES: NA.22

Properties

• vapor density: 3.89 (vs air)
• Quality Level: 100
• vapor pressure: 40 mmHg ( 19.4 °C)
• assay: 99%
• form: liquid
• autoignition temp.: 1035 °F
• expl. lim.: 14.5 %
• refractive index: n20/D 1.439 (lit.); n20/D 1.439
• bp: 95-96 °C (lit.)
• mp: −100 °C (lit.)
• density: 1.156 g/mL at 25 °C (lit.)
• SMILES string: CC(Cl)CCl
• InChI: 1S/C3H6Cl2/c1-3(5)2-4/h3H,2H2,1H3
• InChI key: KNKRKFALVUDBJE-UHFFFAOYSA-N

Description

Application

1,2-Dichloropropane can be used as a building block to synthesize:

•  2-Ylidene-1,3-dithiolane derivatives via one-pot reaction with carbon disulfide and active methylene compounds in the presence of sodium ethylate.      
• β-Chloropropylsulfurs by controllable dechloro-coupling reaction with thiols.      
• Thiazolidine and 1,3-thiazinane derivatives via [3+2] and [3+3] annulation reaction with β-ketothioamides in the presence of phosphonium ylide as a catalyst.

Safety Information

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H302,H331,H350
• pcodes: P202 - P210 - P233 - P301 + P312 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Flam. Liq. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 59.0 °F - closed cup
• flash_point_c: 15.0 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter