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71631

Sigma-Aldrich

Sodium bicarbonate

tested according to Ph. Eur.

Synonym(s):

Natrii hydrogenocarbonas, Sodium hydrogen carbonate

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About This Item

Linear Formula:
NaHCO3
CAS Number:
Molecular Weight:
84.01
Beilstein/REAXYS Number:
4153970
EC Number:
MDL number:
UNSPSC Code:
12352300
PubChem Substance ID:
NACRES:
NA.21

agency

USP/NF
tested according to Ph. Eur.

Quality Level

assay

99.0-101.0%

form

solid

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

solubility

water: soluble 50 g/L

density

2.16 g/mL at 25 °C (lit.)

SMILES string

[Na+].OC([O-])=O

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

InChI key

UIIMBOGNXHQVGW-UHFFFAOYSA-M

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Application


  • Lyophilized rumen fluid as a ruminal fermentation modifier in high grain-fed acidotic goats.: This research examines the effects of sodium bicarbonate on the rumen fluid of goats, particularly in acidosis prevention under high grain diets. It underscores its importance in veterinary science and animal nutrition, providing a preventive measure against digestive disorders in livestock (A Ruba Nanthini et al., 2024).

  • Response of photosynthetic characteristics and antioxidant system in the leaves of safflower to NaCl and NaHCO(3).: This paper focuses on the biochemical responses of safflower leaves to sodium bicarbonate and sodium chloride treatments. The findings highlight how sodium bicarbonate can mitigate salt stress effects, enhancing understanding of plant physiology under stress conditions (Song L et al., 2024).

  • Atomic force microscopy in mechanical measurements of single nanowires.: In this study, sodium bicarbonate is used in preparing samples for atomic force microscopy, demonstrating its utility in high-precision scientific measurements. The research enhances our understanding of material properties at the nanoscale, crucial for developing nanotechnology applications (Pruchnik BC et al., 2024).

Biochem/physiol Actions

Sodium bicarbonate can be used to treat salicylate poisoning.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Salicylate toxicity from genital exposure to a methylsalicylate-containing rubefacient
Thompson TM, et al.
The Western Journal of Medicine, 17(2), 181-181 (2016)
Shay P McGuinness et al.
Critical care medicine, 41(7), 1599-1607 (2013-05-21)
Cardiac surgery-associated acute kidney injury occurs in up to 50% of patients and is associated with increased mortality and morbidity. This study aimed to discover if perioperative urinary alkalinization with sodium bicarbonate infusion reduces the prevalence of cardiac surgery-associated acute
Michael Haase et al.
PLoS medicine, 10(4), e1001426-e1001426 (2013-04-24)
Preliminary evidence suggests a nephroprotective effect of urinary alkalinization in patients at risk of acute kidney injury. In this study, we tested whether prophylactic bicarbonate-based infusion reduces the incidence of acute kidney injury and tubular damage in patients undergoing open
Somjot S Brar et al.
Clinical journal of the American Society of Nephrology : CJASN, 4(10), 1584-1592 (2009-08-29)
Infusion of sodium bicarbonate has been suggested as a preventative strategy but reports are conflicting on its efficacy. The aim of this study was to assess the effectiveness of hydration with sodium bicarbonate for the prevention of contrast-induced acute kidney
Eric A J Hoste et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 25(3), 747-758 (2009-08-26)
There have been conflicting reports on the use of intravenous administration of sodium bicarbonate for prevention of contrast-induced acute kidney injury (CI-AKI). The aim of this study was to evaluate the use of sodium bicarbonate for prevention of CI-AKI. This

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