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Silica gel

high-purity grade, 40, 35-70 mesh, for column chromatography

CAS Number:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


for column chromatography
high-purity grade


powder or crystals


LPLC: suitable



matrix active group


particle size

0.2-0.5 mm (35-70 mesh ASTM)
35-70 mesh

pore size

90 Å mean pore size

surface area

350 m2/g


2230 °C


>1600 °C

separation technique

hydrophilic interaction (HILIC)

SMILES string




InChI key


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General description

Silica gel is a rigid 3D network of colloidal silica. It is exclusively used as a support material for the active titanium (III) centers in Ziegler-Natta catalysts. Silica gel allows a controlled fragmentation leading to form uniform polymer particles with narrow particle size distribution and high bulk density. Silica gel is classified as below:
a. Aquagel - pores are filled with water
b. Xerogel - by the process of evaporation, aqueous phase in the pores are removed
c. Aerogel - solvent removed by supercritical extraction


It has been used for the solid phase extraction (SPE) fractionation of organohalogen compounds in biological organ tissues. Silica gel column may be employed for the clean-up procedures in multiresidue methods of pesticide analyses and as a support for the fabrication of pentachlorophenol (PCP)-imprinted functionalized sorbents for the analysis of trace pentachlorophenol in water samples by SPE combined with high performance liquid chromatography (HPLC).
Silica gel may be used in separation of single-walled carbon nanotube (SWNT) by simple filtration.

Storage Class Code

11 - Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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Development of an accelerated solvent extraction and gel permeation chromatography analytical method for measuring persistent organohalogen compounds in adipose and organ tissue analysis.
Saito, et al.
Chemosphere, 57(5), 373-381 (2004)
Preparation and evaluation of a molecularly imprinted sol-gel material for on-line solid-phase extraction coupled with high performance liquid chromatography for the determination of trace pentachlorophenol in water samples.
Han, et al.
Journal of Chromatography A, 1100(2), 131-136 (2005)
Analyses of pesticides and their metabolites in foods and drinks.
Ahmed, et al.
TrAC, Trends in Analytical Chemistry, 20(11), 649-661 (2001)
Christopher A Dyke et al.
Journal of the American Chemical Society, 127(12), 4497-4509 (2005-03-24)
In this report, procedures are discussed for the enrichment of single-walled carbon nanotube (SWNT) types by simple filtration of the functionalized SWNTs through silica gel. This separation uses nanotube sidewall functionalization employing two different strategies. In the first approach, a
A simple method for production of pure silica from rice hull ash
Kalapathy, U., A. Proctor, and J. Shultz.
Bioresource Technology, 73, 257-262 (2000)

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