717177

Silica gel

technical grade, pore size 60 Å, 70-230 mesh, 63-200 μm

• CAS Number: 112926-00-8
• EC Number: 231-545-4
• MDL number: MFCD00011232
• UNSPSC Code: 12352309
• PubChem Substance ID: 329763461
• NACRES: SB.52

Properties

• grade: technical grade
• Quality Level: 100
• form: powder
• manufacturer/tradename: Sigma-Aldrich
• technique(s): LPLC: suitable
• surface area: ≥480 m²/g , approx.
• matrix: Silica
• matrix active group: silica
• particle size: 63-200 μm; 70-230 mesh
• pore size: 0.7-0.85 cm³/g pore volume (approx.); 60 Å
• bp: 2230 °C
• mp: >1600 °C
• separation technique: hydrophilic interaction (HILIC)
• SMILES string: O=[Si]=O
• InChI: 1S/O2Si/c1-3-2
• InChI key: VYPSYNLAJGMNEJ-UHFFFAOYSA-N

Description

Application

• Chromatographic Separation: Silica gel is widely used as a stationary phase in chromatography for the separation of various chemical compounds. Innovations in silica gel modification, such as pentabromobenzyl group-modified silica gel, have enhanced the separation efficiency for metabolites like nicotinamide. This application is critical for pharmaceutical analysis and metabolomics studies, providing high precision and accuracy in the quantification of biologically relevant molecules (Ozaki et al., Analytical Biochemistry, 2022).


• Environmental Pollutant Detection: Silica gel is used to create molecularly imprinted polymers (MIPs) that selectively recognize and bind environmental pollutants. A notable application involves the embedding of quantum dots in molecularly imprinted silica gel to detect aminoimidazo-azaarenes (AIAs) in food samples. This method offers high selectivity and sensitivity, making it a powerful tool for food safety and environmental monitoring (Qiao et al., Current Analytical Chemistry, 2021).

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable