All Photos(1)

36932

Supelco

Hexadecyltrimethylammonium bromide

analytical standard

Synonym(s):
CTAB, Cetrimonium bromide, Cetyltrimethylammonium bromide, Palmityltrimethylammonium bromide
Linear Formula:
CH3(CH2)15N(Br)(CH3)3
CAS Number:
Molecular Weight:
364.45
Beilstein:
3598189
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

analytical standard

description

cationic

assay

98-102%

form

neat

shelf life

limited shelf life, expiry date on the label

mol wt

364.45 g/mol

application(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

248-251 °C (lit.)

solubility

H2O: soluble 36.4 g/L at 20 °C (completely)

Featured Industry

Cleaning Products
Cosmetics
Environmental
Food and Beverages
Personal Care

format

neat

SMILES string

[Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C

InChI

1S/C19H42N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1

InChI key

LZZYPRNAOMGNLH-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

General description

Cetrimonium bromide(CTAB) is a quaternary ammonium derivative known to enhance anti-tumor activity. It is one of the components of the broad-spectrum antiseptic cetrimide and may also be used as a buffer for DNA extraction.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
CTAB may be used as a reference standard for the determination of:
  • CTAB in various water samples by combining a dispersive liquid-liquid microextraction (DLLME) technique with high performance liquid chromatography.
  • CTAB in pharmaceutical formulations by reversed-phase high-performance liquid chromatography (RP- HPLC).

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT RE 2 Oral - STOT SE 3

Target Organs

Gastrointestinal tract, Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

471.2 °F - closed cup

Flash Point(C)

244 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Potential use of cetrimonium bromide as an apoptosis-promoting anti-cancer agent for head and neck cancer
Ito E, et al.
Molecular Pharmacology (2009)
Development and validation of RP-HPLC method for cetrimonium bromide and lidocaine determination.
Malenovic A, et al.
Il Farmaco (Societa Chimica Italiana : 1989), 60(2), 157-161 (2005)
Journal of Applied Chemistry Application of dispersive liquid-liquid microextraction and high-performance liquid chromatography for the determination of cetrimonium bromide in water samples.
Rajabi M and Ghazaghi M
J. Appl. Chem., 8(27) (2013)
Sebastien Fraud et al.
Antimicrobial agents and chemotherapy, 52(12), 4478-4482 (2008-10-08)
The biocide chlorhexidine (CHX) as well as additional membrane-active agents were shown to induce expression of the mexCD-oprJ multidrug efflux operon, dependent upon the AlgU stress response sigma factor. Hyperexpression of this efflux system in nfxB mutants was also substantially...
Lourdes Pérez et al.
European journal of medicinal chemistry, 44(5), 1884-1892 (2008-12-17)
Biocompatible cationic surfactants from the amino acid lysine (hydrochloride salts of N(epsilon)-lauroyl lysine methyl ester, N(epsilon)-myristoyl lysine methyl ester and N(epsilon)-palmitoyl lysine methyl ester) have been prepared in high yields by lysine acylation in epsilon position with three natural saturated...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service