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31493

Sigma-Aldrich

Sodium salicylate

puriss. p.a., reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance)

Synonym(s):
2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt, Sodium 2-hydroxybenzoate
Linear Formula:
HOC6H4COONa
CAS Number:
Molecular Weight:
160.10
Beilstein:
3732792
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Agency

USP/NF
reag. Ph. Eur.

Quality Level

grade

puriss. p.a.

assay

99.5-101.0% (calc. to the dried substance)

impurities

acidic reac. impurities, complies
sulfite or thiosulfate, complies
≤0.001% heavy metals (as Pb)

loss

≤0.3% loss on drying, 105 °C

mp

>300 °C (lit.)

anion traces

chloride (Cl-): ≤20 mg/kg
sulfate (SO42-): ≤500 mg/kg

cation traces

Fe: ≤10 mg/kg

suitability

in accordance for appearance of solution

SMILES string

[Na+].Oc1ccccc1C([O-])=O

InChI

1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1

InChI key

ABBQHOQBGMUPJH-UHFFFAOYSA-M

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General description

Sodium salicylate can be prepared from the reaction of salicylic acid and ammonia. It exhibits fluorescence at higher concentrations and effectively absorbs β-particles. Due to these properties, it has been employed as fluor for the radioactivity detection in various gels.

Application

Sodium salicylate may be used as phenolic reagent in salicylate method for the determination of ammonia. It may be employed as a hydrotropic agent to study the release of anticancer drug camptothecin (CPT) from the mixed micelles [composed of Pluronic P105 (P105) and D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS)].

Pictograms

Exclamation markHealth hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

208.9 °F - Pensky-Martens closed cup

Flash Point(C)

98.3 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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