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Oenothein B

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C68H48O44
CAS Number:
104987-36-2
Molecular Weight:
1569.08
UNSPSC Code:
85151701
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥80% (HPLC)

shelf life

limited shelf life, expiry date on the label

application(s)

food and beverages

format

neat

storage temp.

2-8°C

InChI

1S/C68H50O44/c69-22-1-14(2-23(70)39(22)79)59(93)109-56-52(92)68(112-61(95)16-5-26(73)41(81)27(74)6-16)106-34-13-103-63(97)20-11-32(46(86)50(90)38(20)37-19(64(98)107-54(34)56)9-30(77)44(84)49(37)89)104-53-21(10-31(78)45(85)51(53)91)66(100)111-58-57(110-60(94)15-3-24(71)40(80)25(72)4-15)55-33(105-67(58)101)12-102-62(96)17-7-28(75)42(82)47(87)35(17)36-18(65(99)108-55)8-29(76)43(83)48(36)88/h1-11,33-34,52,54-58,67-92,101H,12-13H2

InChI key

SHYSVHSGJVNSLX-UHFFFAOYSA-N

General description

Oenothein B is a dimeric ellagitannin compound which is found commonly in genusOenothera.

Application

Oenothein B may be used as a reference standard for the determination of oenothein B in aqueous extracts of Epilobii angustifolli herba and Epilobium angustifolium L. by high performance thin-layer chromatography (HPTLC)-densitometry, in plant materials by HPLC combined with diode array detector (DAD) and mass spectrometry (MS) and in Eucalyptus globulus leaves by HPLC-DAD coupled to electrospray ionization (EIS) MS.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG8566
BCCG0097
BCCD7964
BCCD2416
BCBZ7599

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K Aoki et al.
Biochemical and biophysical research communications, 210(2), 329-337 (1995-05-16)
Oenothein B, a macrocircular dimeric ellagitannin, was found to be a potent and specific inhibitor of poly(ADP-ribose) glycohydrolase. Oenothein B suppressed glucocorticoid-sensitive mouse mammary tumor virus (MMTV) transcription in 34I cells. This suppression was accompanied by inhibition of glucocorticoid-induced endogeneous
Sebastian Granica et al.
Phytochemical analysis : PCA, 23(6), 582-587 (2012-03-08)
Oenothein B (OeB) is a dimeric macrocyclic ellagitannin occurring mainly in the genus Oenothera. In the literature no validated HPLC method for quantification of this compound has been reported. To develop and validate an efficient HPLC method for quantification of
D Lesuisse et al.
Journal of natural products, 59(5), 490-492 (1996-05-01)
Several extracts from Epilobium parviflorum, a plant used in Central Europe for the treatment of prostate disorders, were evaluated in a biochemical assay with 5-alpha-reductase. The aqueous extract displaying inhibition of the enzyme was analyzed, the fraction responsible for this
Improved and Validated HPTLC Method for Quantification of Oenothein B and its Use for Analysis of Epilobium angustifolium L.
Shikov, et al.
Journal of Planar Chromatography--Modern TLC, 23(1), 70-74 (2010)
Hideharu Maruta et al.
Biological & pharmaceutical bulletin, 30(3), 447-450 (2007-03-03)
The formation of ATP produced from poly(ADP-ribose) [(ADP-R)n] has been suggested to be required to repair damaged DNA. Here we investigate whether this ATP is involved in DNA replication processes during DNA repair. Poly(ADP-ribosyl)ated mid-S phase cell nuclei, which were
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