MABN85

Anti-CORO1A Antibody, clone 2E11.2

clone 2E11.2, from mouse

• Synonym(s): Coronin-1A, Coronin-like protein A, Clipin-A, Coronin-like protein p57, Tryptophan aspartate-containing coat protein, TACO
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 2E11.2, monoclonal
• species reactivity: mouse, human
• technique(s): immunocytochemistry: suitable; western blot: suitable
• isotype: IgG1κ
• NCBI accession no.: NP_001180262
• UniProt accession no.: P31146
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: mouse ... Coro1A(12721)

Description

General description

Coronin-1A (CORO1A) is also called Coronin-like protein A (Clipin-A), Coronin-like protein p57, and Tryptophan aspartate-containing coat protein (TACO). CORO1A is likely a critical cytoskeleton component in highly motile cells that is involved in invagination and forming protrusions of the plasma membrane to facilitate cell movement. CORO1A is expressed in brain, thymus, spleen, bone marrow and lymph nodes.

Immunogen

Epitope: C-terminus

GST-tagged recombinant protein corresponding to the C-terminus of human CORO1A.

Application

Detect Coronin using this mouse monoclonal antibody, Anti-CORO1A Antibody, clone 2E11.2 validated for use in western blotting & ICC.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Western Blotting Analysis: 2.0 µg/mL from a representative lot detected CORO1A in 10 µg of NIH3T3 cell lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected CORO1A in human cerebral cortex issue.

Quality

Evaluated by Western Blotting in Raji cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected CORO1A in 10 µg of Raji cell lysate.

Target description

~51 kDa observed

Physical form

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable