ABN38

Anti-RAB35 Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Ras-related protein Rab-35, GTP-binding protein RAY, Ras-related protein Rab-1C
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: rat, human, horse
• species reactivity (predicted by homology): canine (based on 100% sequence homology), equine (based on 100% sequence homology)
• technique(s): immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBI accession no.: NP_006852
• UniProt accession no.: Q15286
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... RAB35(11021)

Description

General description

RAB35 is a member of the Rab GTPases identified in the human genome. It is ubiquitously expressed and regulates a fast endocytotic recycling events associated with the terminal steps of cytokinesis, the formation of immunological synapse, and peptide loading onto major histocompatibility complex III molecules. RAB35 also plays a significant role in the formation of the immunological synapse (IS) between peptide-loaded antigen presenting cells (APCs) and T cells.

Specificity

This antibody recognizes RAB35 at the C-terminus.

Immunogen

KLH-conjugated linear peptide corresponding to the C-terminus of human RAB35.

Application

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected RAB35 in normal human brain tissue.

This Anti-RAB35 Antibody is validated for use in WB, IH(P) for the detection of RAB35.

Quality

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected RAB35 on 10 µg of human brain tissue lysate.

Target description

~19 kDa observed. The calculated molecular weight is 23 kDa

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable