AB1583
Anti-Neuropeptide Y Antibody
serum, Chemicon®
Synonym(s):
NPY
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
sheep
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
invertebrates, rabbit, guinea pig
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
radioimmunoassay: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
rabbit ... Npy(100301542)
Specificity
Neuropeptide Y (NPY). The specificity was determined by RIA. Synthetic peptides somatostatin-14, leu-enkephalin, met-enkephalin, oxytocin, Agr8-vasopressin, vasoactive intestinal peptide and angiotensin II showed less than 0.005% cross reactivity and substance P less than 0.02%. Peptide YY and bovine pancreatic polypeptide showed approximately 36% and 0.05% cross reactivity respectively. Human Peptide YY shares 65% homology amino acid sequence for human NPY.
Synthetic NPY completely abolishes radio labeled NPY binding to NPY antibody in RIA and antibody binding to tissue antigen.
Synthetic NPY completely abolishes radio labeled NPY binding to NPY antibody in RIA and antibody binding to tissue antigen.
Immunogen
Synthetic NPY peptide conjugated to bovine thyroglobulin.
Application
Detect Neuropeptide Y using this Anti-Neuropeptide Y Antibody validated for use in IH, RIA.
Immunohistochemistry: 1:5,000 on rabbit and guinea pig using an ABC detection method.
RIA
Optimal working dilutions must be determined by the end user.
RIA
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
CNS Control of Metabolism
Hormones & Receptors
CNS Control of Metabolism
Hormones & Receptors
Physical form
Sheep serum. Lyophilized, no preservatives. Reconstitute with 100 μL of sterile distilled water.
Storage and Stability
Maintain at -20 to -70°C in undiluted aliquots for up to one year. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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J A Evans et al.
Neuroscience, 202, 300-308 (2011-12-14)
In mammals, light entrains the central pacemaker within the suprachiasmatic nucleus (SCN) through both a direct neuronal projection from the retina and an indirect projection from the intergeniculate leaflet (IGL) of the thalamus. Although light comparable in intensity to moonlight
Quantitative study of NPY-expressing GABAergic neurons and axons in rat spinal dorsal horn.
Polgar E, Sardella TC, Watanabe M, Todd AJ
The Journal of Comparative Neurology null
Darren Cameron et al.
Pain, 156(10), 2061-2071 (2015-06-24)
The anterolateral tract (ALT), which originates from neurons in lamina I and the deep dorsal horn, represents a major ascending output through which nociceptive information is transmitted to brain areas involved in pain perception. Although there is detailed quantitative information
Alexander V Loktev et al.
Cell reports, 5(5), 1316-1329 (2013-12-10)
Human monogenic obesity syndromes, including Bardet-Biedl syndrome (BBS), implicate neuronal primary cilia in regulation of energy homeostasis. Cilia in hypothalamic neurons have been hypothesized to sense and regulate systemic energy status, but the molecular mechanism of this signaling remains unknown.
The relationship of the birth date of rat sympathetic neurons to the target they innervate.
Chubb DP, Anderson CR
Developmental Dynamics null
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