ZRB1042
Anti-Somatostatin-28 Antibody, clone 2B19 ZooMAb® Rabbit Monoclonal
recombinant, expressed in HEK 293 cells
Synonym(s):
Growth hormone release-inhibiting factor, Somatostatin
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
recombinant
expressed in HEK 293 cells
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
2B19, recombinant monoclonal
monoclonal
product line
ZooMAb® learn more
form
lyophilized
mol wt
calculated mol wt 12.73 kDa (for Somatostatin)
species reactivity
human
species reactivity (predicted by homology)
rat, sheep, bovine, mouse
packaging
antibody small pack of 25 μL
greener alternative product characteristics
Waste Prevention
Designing Safer Chemicals
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
enhanced validation
recombinant expression
Learn more about Antibody Enhanced Validation
sustainability
Greener Alternative Product
technique(s)
affinity binding assay: suitable
immunofluorescence: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
isotype
IgG
UniProt accession no.
greener alternative category
shipped in
ambient
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... SST(6750)
General description
We are committed to bringing you greener alternative products, which adhere to one or more of The 12 Principles of Green Chemistry.This antibody is Preservative-free, produced without the harm or sacrifice of animals and exceptionally stable to allow for ambient shipping and storage if needed and thus aligns with "Waste Prevention", "Designing Safer Chemicals" and "Design for Energy Efficiency". Click here for more information.
ZooMAb antibodies represent an entirely new generation of recombinant monoclonal antibodies.
Each ZooMAb antibody is manufactured using our proprietary recombinant expression system, purified to homogeneity, and precisely dispensed to produce robust and highly reproducible lot-to-lot consistency. Only top-performing clones are released for use by researchers. Each antibody is validated for high specificity and affinity across multiple applications, including its most commonly used application. ZooMAb antibodies are reliably available and ready to ship when you need them.
Learn more about ZooMAb here.
Each ZooMAb antibody is manufactured using our proprietary recombinant expression system, purified to homogeneity, and precisely dispensed to produce robust and highly reproducible lot-to-lot consistency. Only top-performing clones are released for use by researchers. Each antibody is validated for high specificity and affinity across multiple applications, including its most commonly used application. ZooMAb antibodies are reliably available and ready to ship when you need them.
Learn more about ZooMAb here.
Specificity
Clone 8G9.2 is a ZooMAb mouse recombinant monoclonal antibody that specifically detects human Somatstatin-28.
Immunogen
KLH-conjugated linear peptide corresponding to 17 amino acids from human Somatistatin-28 (C-terminal region of somatostatin).
Application
Anti-Somatostatin-28, clone 2B19 ZooMAb, Cat. No. ZRB1042, is a recombinant Rabbit monoclonal antibody that targets Somatostatin-28 and is tested for use in Affinity Binding Assay, Immunofluorescence, and Immunohistochemistry (Paraffin).
Immunofluorescence Analysis: A 1:100 dilution from a representative lot detected Somatostatin-28 in human pancreas tissue sections.
Affinity Binding Assay: A representative lot of this antibody bound human Somatostatin-28 peptide with a KD of 1.1 x 10-7 in an affinity binding assay.
Note: Actual optimal working dilutions must be determined by end user as specimens, and experimental conditions may vary with the end user
Affinity Binding Assay: A representative lot of this antibody bound human Somatostatin-28 peptide with a KD of 1.1 x 10-7 in an affinity binding assay.
Note: Actual optimal working dilutions must be determined by end user as specimens, and experimental conditions may vary with the end user
Target description
Somatostatin (UniProt: P61278; also known as Growth hormone release-inhibiting factor) is encoded by the SST gene (Gene ID: 6750) in human. Somatostatin, a tetradecapeptide, displays highest expression in the islets of Langerhans and in the brain. It is synthesized with a signal peptide (aa 1-24), which is subsequently cleaved off and the remaining chain can cleave into three chains: Neuronostatin (aa 31-43), Somatostatin-28 (aa 89-116), and Somatostatin-14 (aa 103-116). Somatostatin-28 is mainly produced by the intestinal enteroendocrine cells and somatostatin-14 is the predominant form present in the brain. Neuronostatin is believed to enhance low-glucose-induced glucagon release by pancreatic alpha cells. Somatostatin is shown to Inhibit the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. In the intestine it exerts inhibitory effects on various gastrointestinal functions, including gastric acid secretion, gastric emptying, intestinal motility, and release of various gastrointestinal hormones. Somatostatin actions are mediated through five distinct receptor subtypes known as SST1-5 that are G-protein coupled receptors. SST2 and 5 are shown to be the main mediators of the gastrointestinal effects of somatostatin. This ZooMAb recombinant monoclonal antibody, generated by our propriety technology, offers significantly enhanced specificity, affinity, reproducibility, and stability over conventional monoclonals.
Physical form
Purified recombinant rabbit monoclonal antibody IgG, lyophilized in PBS with 5% Trehalose, normal appearance a coarse or translucent resin. Contains no biocide or preservatives, such as azide, or any animal by-products. Larger pack sizes provided as multiples of 25 μL.
Reconstitution
30 μg/mL after reconstitution at 25 μL per vial. Please refer to guidance on suggested starting dilutions and/or titers per application and sample type.
Storage and Stability
Recommend storage of lyophilized product at 2-8°C; Before reconstitution, micro-centrifuge vials briefly to spin down material to bottom of the vial; Reconstitute each vial by adding 25 μL of filtered lab grade water or PBS; Reconstituted antibodies can be stored at 2-8°C, or -20°C for long term storage. Avoid repeated freeze-thaws.
Legal Information
ZooMAb is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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