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Key Documents

AB1532P

Sigma-Aldrich

Anti-Neurotrophin 3 Antibody

Chemicon®, from rabbit

Synonym(s):

NT3

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat, human, chicken

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NM_001102654.1
NM_002527.4

UniProt accession no.

P20783

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... NTF3(4908)

Specificity

Neurotrophin 3 (NT3). Less than 0.1% cross reactivity with recombinant human BDNF, recombinant human NT4 and mouse NGF.

Immunogen

An 11 amino acid peptide corresponding to the amino-terminal of mouse Neurotrophin 3 (NT3) coupled to BSA. The sequence is H2N-YAEHKSHRGEY-.

Application

Detect Neurotrophin 3 using this Anti-Neurotrophin 3 Antibody validated for use in WB, IH.
Immunohistochemistry: 1-10 μg/mL (see suggested protocol).


Immunoblotting:1-10 μg/mL


Inhibition of biological activity in vitro: 1-10 μg/mL


In vivo animal studies


Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins

Physical form

Affinity purified immunoglobulin. Lyophilized from PBS, no preservatives. Reconstitute to desired volume with sterile distilled water. Suggested concentration 0.5-1 mg/mL.

Storage and Stability

Maintain at -20 to -70°C in undiluted aliquots for up to one year. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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X F Zhou et al.
The Journal of comparative neurology, 363(1), 69-77 (1995-12-04)
Sensory neurons can be classified into subpopulations based on a variety of characteristics, including their morphology and physiological modalities. Whether any of these classifications correlates with neurotrophic sensitivities has not been determined. We have recently reported that a subpopulation of
Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function
Elkabes, S, et al
The Journal of Neuroscience, 16, 2508-2521 (1996)
Localization of neurotrophin-3-like immunoreactivity in the rat central nervous system.
Zhou, X F and Rush, R A
Brain Research, 643, 162-172 (1994)
Huan Liu et al.
Experimental neurology, 241, 125-137 (2012-12-25)
The olfactory system continuously incorporates new neurons into functional circuits throughout life. Axons from olfactory sensory neurons (OSNs) in the nasal cavity synapse on mitral, tufted and periglomerular (PG) cells in the main olfactory bulb, and low levels of turnover

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