8.21881

Polyethylene glycol

10000, for synthesis

• Synonym(s): Poly(ethylene glycol), Polyethylene glycol 10000, Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 10000, PEG
• Linear Formula: H(OCH₂CH₂)_nOH
• CAS Number: 25322-68-3
• MDL number: MFCD00081839
• UNSPSC Code: 13111021
• EC Index Number: 500-038-2
• NACRES: NA.22

Properties

• vapor pressure: <0.01 hPa ( 20 °C)
• Quality Level: 200
• form: liquid
• autoignition temp.: 340 °C
• potency: 28000 mg/kg LD₅₀, oral (Rat); >20000 mg/kg LD₅₀, skin (Rabbit)
• pH: 5-7 (20 °C, 100 g/L in H₂O)
• kinematic viscosity: 500-900 cSt(20 °C)
• mp: 58-63 °C
• transition temp: flash point 265 °C
• density: 1.2 g/cm³ at 20 °C
• bulk density: 400‑500 kg/m³
• storage temp.: no temp limit
• SMILES string: C(CO)O
• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
• InChI key: LYCAIKOWRPUZTN-UHFFFAOYSA-N

Description

General description

Polyethylene glycol (PEG) is a synthetic, hydrophilic, biocompatible polymer that has a wide range of uses in PEGylation, surface conjugation, nanoparticle coating, and crosslinking for hydrogels. PEGs are made by polymerizing ethylene oxide via a ring-opening reaction to produce a wide range of molecular weights and molecular weight distributions (polydispersity).

Application

Polyethylene glycol 10000 can be used as a surfactant in the synthesis of Ni₁₂P₅ hollow microspheres via the hydrothermal method in the presence of hexamethylenetetramine (HMT). PEG 10000 significantly improves the formation of high-quality hollow microspheres, without this surfactant morphology is near-spherical particles.
It can also be used as:

• A reactant to synthesize N-PEGylated-thiazolium salt, which is used as an organocatalyst for the benzoin condensation.
• A nonionic dispersive agent in the preparation Nd₂Si₂O₇ ceramic pigment by a co-precipitation method.

Analysis Note

Melting range (lower value): ≥ 59 °C
Melting range (upper value): ≤ 64 °C
Hydroxyl value: 9 - 12
Average molecular mass: 9000 - 12500
Identity (IR): passes test

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: 281.5 °F - closed cup
• flash_point_c: 138.6 °C - closed cup