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557303

Sigma-Aldrich

Rifampicin - CAS 13292-46-1 - Calbiochem

Antibiotic that specifically inhibits DNA-dependent RNA polymerase in bacteria by forming an inactive complex.

Synonym(s):
Rifampicin - CAS 13292-46-1 - Calbiochem, Rifampin, 3-(4-Methylpiperazinyliminomethyl)rifamycin SV
Empirical Formula (Hill Notation):
C43H58N4O12
CAS Number:
Molecular Weight:
822.94
MDL number:

Quality Level

assay

≥97% (by Assay)

form

powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

brown-red to brick red

solubility

DMSO: 25 mg/mL
methanol: 25 mg/mL

shipped in

ambient

storage temp.

10-30°C

General description

Antibiotic that specifically inhibits DNA-dependent RNA polymerase in bacteria by forming an inactive complex. Does not affect mammalian RNA polymerase. Inhibits transcription by preventing the initial transcription complex from entering the elongation mode.
Antibiotic that specifically inhibits DNA-dependent bacterial RNA polymerase by forming an inactive complex with RNA polymerase. Does not affect mammalian RNA polymerase. Inhibits transcription by preventing the initial transcription complex from entering the elongation mode.

Packaging

5 g in Plastic ampoule

Biochem/physiol Actions

Primary Target
DNA-dependent RNA polymerase in bacteria

Warning

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). DMSO stock solutions are stable for up to 2 months at -20°C.

Other Notes

Jin, D.J. and Turnbough, Jr., C.L. 1994. J. Mol. Biol. 236, 72.
Levin, M.E. and Hatfull, G.F. 1993. Mol. Microbiol. 8, 277.
Wehrli, W., et al. 1968. Proc. Natl. Acad. Sci. USA61, 667.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Lact. - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Quality

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