5.43838

Sodium phosphate dibasic

anhydrous for HPLC LiChropur^™

• Synonym(s): Sodium phosphate dibasic, di-Sodium hydrogen phosphate anhydrous, sec-Sodium phosphate, Disodium hydrogen phosphate, Disodium phosphate, Sodium hydrogenphosphate
• Linear Formula: Na₂HPO₄
• CAS Number: 7558-79-4
• Molecular Weight: 141.96
• MDL number: MFCD00003496
• UNSPSC Code: 41116105
• EC Index Number: 231-448-7
• NACRES: NB.21

Properties

• grade: anhydrous
• Quality Level: 100
• form: solid
• technique(s): HPLC: suitable
• pH: 8.7-9.3 (20 °C, 10 g/L in H₂O)
• pKa (25 °C): (1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)
• mp: 250 °C
• solubility: 77 g/L
• bulk density: 880 kg/m³
• storage temp.: 2-30°C
• SMILES string: [Na+].[Na+].[H]OP([O-])([O-])=O
• InChI: 1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2
• InChI key: BNIILDVGGAEEIG-UHFFFAOYSA-L

Description

Application

• Synchronized separation of seven medications representing most commonly prescribed antihypertensive classes by using reversed-phase liquid chromatography: Application for analysis in their combined formulations.: This study utilizes sodium phosphate dibasic in the reversed-phase liquid chromatography process to analyze and separate multiple antihypertensive drugs in combined formulations, enhancing the precision and efficiency of pharmaceutical analysis (Ebeid et al., 2014).


• [Study of the acupuncture effect on monoamine transmitters in rabbit plasma and brain tissue by high performance liquid chromatography with electrochemical detection].: Sodium phosphate dibasic was used as a buffering agent in the HPLC method to study the effects of acupuncture on monoamine levels in rabbit plasma and brain tissue, providing insights into biochemical responses to traditional Chinese medicine treatments (Hou et al., 2002).


• The effect of formulation on reduced radioiodide thyroid uptake.: This research explores the role of sodium phosphate dibasic in the formulation of radiopharmaceuticals, specifically its impact on thyroid uptake of radioiodide, with implications for improving diagnostic and therapeutic applications in nuclear medicine (Yu et al., 2002).

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Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable