444225
MMP-3 Inhibitor II
The MMP-3 Inhibitor II, also referenced under CAS 161314-17-6, controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Synonym(s):
MMP-3 Inhibitor II, N-Isobutyl-N-(4-methoxyphenylsulfonyl)-glycylhydroxamic Acid, NNGH
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About This Item
Empirical Formula (Hill Notation):
C13H20N2O5S
CAS Number:
Molecular Weight:
316.37
MDL number:
UNSPSC Code:
12352200
Recommended Products
Quality Level
assay
≥98% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
DMSO: 30 mg/mL
ethanol: 8 mg/mL
shipped in
ambient
storage temp.
10-30°C
General description
A cell-permeable, potent inhibitor of human MMP-3 (stromelysin; Ki = 130 nM).
A potent and cell-permeable inhibitor of human MMP-3 (Ki = 130 nM).
Biochem/physiol Actions
Cell permeable: yes
Primary Target
human MMP-3
human MMP-3
Product does not compete with ATP.
Reversible: no
Target Ki: 130 nM against human MMP-3
Warning
Toxicity: Standard Handling (A)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Kato, N., et al. 2002. Genome Informatics13, 272.
MacPherson, L.J., et al. 1997. J. Med. Chem. 40, 2525.
MacPherson, L.J., et al. 1997. J. Med. Chem. 40, 2525.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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