407135-M

Caged Ins(1,4,5)P₃, Trisodium Salt

Photolabile derivative of Ins(1,4,5)P₃ that is not biologically active and is not metabolized by endogenous phosphatase.

• Synonym(s): Caged Ins(1,4,5)P₃, Trisodium Salt, D- myo-Inositol 1,4,5-Trisphosphate, P ⁴⁽⁵⁾-1-(2-Nitrophenyl)ethyl Ester, 3Na
• Empirical Formula (Hill Notation): C₁₄H₁₉NO₁₇P₃ · 3Na
• Molecular Weight: 635.19
• UNSPSC Code: 12352211

Properties

• Quality Level: 100
• assay: ≥90% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated; protect from light
• color: off-white
• solubility: water: 1 mg/mL
• storage temp.: −20°C

Description

General description

Extinction coefficient (265 nm, H₂O): 4240 M^-1cm^-1.

Note: 1 set = 10 x 10 µg.

Photolabile derivative of Ins(1,4,5)P₃ that is not biologically active and is not metabolized by endogenous phosphatase (extinction coefficient: 4240 M^-1cm^-1; 265 nm, H₂O). A mixture of two isomers with a cage on either the 4 or 5 position. Can be selectively released by irradiation with a short pulse of light of about 360 nm to produce a concentration jump of Ins(1,4,5)P₃.

Photolabile derivative of Ins(1,4,5)P₃ that is not biologically active and is not metabolized by endogenous phosphatase. A mixture of two isomers with a cage present on either the 4 or 5 position. Can be selectively released by irradiation with a short pulse of light of about 360 nm to produce a concentration jump of Ins(1,4,5)P₃.

Biochem/physiol Actions

Primary Target
Photolabile derivative of Ins(1,4,5)P3 that is not biologically active

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Other Notes

Walker, J.W., et al. 1987. Nature327, 249.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable