I9766
D-myo-Inositol 1,4,5-tris-phosphate trisodium salt
≥95% (by 1H NMR and TLC)
Synonym(s):
Ins(1,4,5)P3
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About This Item
Recommended Products
Quality Level
assay
≥95% (by 1H NMR and TLC)
form
powder
color
white
solubility
H2O: soluble
cation traces
K: <0.2%
Na: 12.5-16.0
storage temp.
−20°C
InChI
1S/C6H15O15P3.3Na/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12;;;/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18);;;/q;3*+1/p-3/t1-,2+,3+,4-,5-,6-;;;/m1.../s1
InChI key
ZVCVTWVBDIPWPZ-ZKVWPJASSA-K
Biochem/physiol Actions
Stimulates intracellular calcium mobilization.
Other Notes
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Molecular cell, 67(4), 711-723 (2017-08-19)
The mitochondrial calcium uniporter complex is essential for calcium (Ca2+) uptake into mitochondria of all mammalian tissues, where it regulates bioenergetics, cell death, and Ca2+ signal transduction. Despite its involvement in several human diseases, we currently lack pharmacological agents for
Organic & biomolecular chemistry, 13(30), 8291-8297 (2015-07-04)
In order to detect small polyanions (sPAs), which play important roles in many biological systems, a triazolium cyclodextrin click cluster (5, hexakis{6-(3-methyl-4-hydroxymethyl-1H-1,2,3-triazolium-1-yl)-6-deoxy}-α-cyclodextrin iodide) was synthesized and characterized. The competition binding to 5 occupied by 5-carboxyfluorescein of inositol-1,4,5-trisphosphate (IP3), phytic acid
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