311204

Nᴳ,NG′-Dimethyl-L-arginine dihydrochloride

≥97% (HPLC), solid, nitric oxide synthesis inhibitor, Calbiochem^®

• Synonym(s): N^G,N^G′-Dimethyl-L-arginine, Dihydrochloride, SDMA, 2HCl
• Empirical Formula (Hill Notation): C₈H₁₈N₄O₂ · 2HCl
• Molecular Weight: 275.18
• UNSPSC Code: 12352209
• NACRES: NA.77

Properties

• product name: N^G,N^G′-Dimethyl-L-arginine, Dihydrochloride, Cell permeable. Endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.
• Quality Level: 100
• assay: ≥97% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; desiccated (hygroscopic)
• color: white to light yellow
• solubility: water: 50 mg/mL
• shipped in: wet ice
• storage temp.: 2-8°C

Description

General description

A cell-permeable endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.

Cell permeable. Endogenous inhibitor of nitric oxide synthesis in vitro and in vivo. Does not exhibit any significant inhibitory effect on NOS activity.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
NOS in vitro

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Other Notes

Nam, S.W., et al. 1998. Arch. Pharm. Res. 21, 128.
Closs, E.I., et al. 1997. Nitric Oxide 1, 65.
Kotani, K., et al. 1992. J. Neurochem.58, 1127.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable