1.07019

Toluene

for analysis EMPARTA^® ACS

• Synonym(s): Toluol, Methylbenzene
• Linear Formula: C₆H₅CH₃
• CAS Number: 108-88-3
• Molecular Weight: 92.14
• Beilstein/REAXYS Number: 635760
• MDL number: MFCD00008512
• UNSPSC Code: 12191501
• EC Index Number: 203-625-9

Properties

• grade: ACS reagent
• Quality Level: 200
• vapor density: 3.2 (vs air)
• vapor pressure: 22 mmHg ( 20 °C); 26 mmHg ( 25 °C)
• product line: EMPARTA^®
• assay: ≥99.5% (GC)
• form: liquid
• autoignition temp.: 997 °F
• expl. lim.: 7 %
• impurities: ≤0.0002 meq/g Acidity; ≤0.0006 meq/g Alkalinity; ≤0.003% Sulfur compounds (as S); ≤0.03% Water
• evapn. residue: ≤0.001%
• color: APHA: ≤10
• refractive index: n/D 1.496 (lit.)
• kinematic viscosity: 0.7 cSt(20 °C)
• bp: 110-111 °C (lit.)
• mp: -93 °C (lit.)
• transition temp: flash point 4 °C
• density: 0.865 g/mL at 25 °C (lit.)
• storage temp.: 2-30°C
• SMILES string: Cc1ccccc1
• InChI: 1S/C7H8/c1-7-5-3-2-4-6-7/h2-6H,1H3
• InChI key: YXFVVABEGXRONW-UHFFFAOYSA-N

Description

Application

• Experimental and Model-Based Approach to Evaluate Solvent Effects on the Solubility of the Pharmaceutical Artemisinin.: This research investigates the role of toluene as a solvent in enhancing the solubility of artemisinin, using both experimental setups and model-based assessments. The findings offer insights into solvent selection for pharmaceutical synthesis, making significant contributions to solvent theory and practical applications in drug formulation (Wünsche S et al., 2024).


• Highly sensitive and selective laser-based BTEX sensor for occupational and environmental monitoring.: Describes the development of a new laser-based sensor using toluene as a calibration standard for BTEX (Benzene, Toluene, Ethylbenzene, Xylene) detection. This sensor offers improved sensitivity and selectivity, crucial for monitoring air quality in occupational and environmental health contexts (Mhanna M et al., 2024).


• Response of microbial communities in aquifers with multiple organic solvent contamination: Implications for MNA remedy.: Explores the ecological impact of toluene and other solvents on microbial communities within aquifers. This study highlights the resilience and adaptability of microorganisms, informing strategies for monitored natural attenuation (MNA) in solvent-contaminated environments (Yang L et al., 2024).


• Elucidating solvent effects on lipase-catalyzed peroxyacid synthesis through activity-based kinetics and molecular dynamics.: Focuses on the use of toluene to understand its effects on enzyme-catalyzed reactions, specifically lipase-mediated peroxyacid synthesis. The study combines kinetic experiments with molecular dynamics simulations, enhancing the understanding of solvent interactions in biocatalysis (Brandolín SE et al., 2024).


• Stability-Indicating TLC-Densitometric and HPLC Methods for Simultaneous Determination of Teneligliptin and Pioglitazone in Pharmaceutical Dosage Forms with Eco-Friendly Assessment.: Utilizes toluene in the development of chromatographic methods for the analysis of pharmaceutical compounds. This research demonstrates toluene′s utility in creating efficient, eco-friendly analytical techniques for drug quantification (Akabari AH et al., 2024).

Packaging

1.07019.2521: 2.5L, Minimum order quantity: 4

Analysis Note

Purity (GC): ≥ 99.5 %
Identity (IR): conforms
Appearance: clear
Color: ≤ 10 Hazen
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0006 meq/g
Boiling point: 109 - 111 °C
Sulfur compounds (as S): ≤ 0.003 %
Readily carbonizable substances: conforms
Evaporation residue: ≤ 0.001 %
Water: ≤ 0.03 %

Legal Information

EMPARTA is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS07,GHS08
• signalword: Danger
• hcodes: H225 - H304 - H315 - H336 - H361d - H373 - H412
• pcodes: P202 - P210 - P273 - P301 + P310 - P303 + P361 + P353 - P331
• Hazard Classifications: Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 39.9 °F
• flash_point_c: 4.4 °C