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M-015

Supelco

Methaqualone solution

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C16H14N2O
CAS Number:
72-44-6
Molecular Weight:
250.30
MDL number:
MFCD00057320
UNSPSC Code:
41116107
PubChem Substance ID:
329817730
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

concentration

1 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

2-8°C

SMILES string

Cc1ccccc1N2C(C)=Nc3ccccc3C2=O

InChI

1S/C16H14N2O/c1-11-7-3-6-10-15(11)18-12(2)17-14-9-5-4-8-13(14)16(18)19/h3-10H,1-2H3

InChI key

JEYCTXHKTXCGPB-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

General description

Methaqualone is a sedative-hypnotic and a central nervous system depressant sold under the trade name Quaalude for treatment of insomnia. Methaqualone also has a history of abuse, known by street names such as Disco biscuits, Lemmons, and 714s. This certified solution standard is applicable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from urine drug testing to forensic analysis and clinical toxicology.

Application


  • Pharmacokinetic studies: The analysis of Methaqualone in pharmacokinetic research employs liquid chromatography/tandem mass spectrometry, crucial for understanding its metabolism and excretion patterns. Such studies are vital for developing safety profiles and therapeutic guidelines for sedative-hypnotics (Yun et al., 2007).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

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signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Reinhard A Uebel et al.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 92(7), 547-549 (2002-08-29)
Urine samples that tested positive for two drugs of abuse, namely cannabis and methaqualone, were reassayed in the presence or absence of common household chemicals: Jik (sodium hypochlorite), Dettol (chloroxylenol), G-cide Plus (glutaraldehyde), Perle Hand Soap, ethanol, isopropanol and peroxide
Mark R Darling et al.
SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, 57(4), 132-135 (2002-06-25)
The effects of cannabis/methaqualone/tobacco smoking on the epithelial cells of the tongue, buccal mucosa and floor of the mouth were examined. Oral mucosal smears for detection of cellular changes were taken from 4 sites in 16 patients. The tongue blade
Meihui Pan et al.
The Journal of biological chemistry, 277(6), 4413-4421 (2001-11-13)
Although microsomal triglyceride transfer protein (MTP) and newly synthesized triglyceride (TG) are critical for co-translational targeting of apolipoprotein B (apoB100) to lipoprotein assembly in hepatoma cell lines, their roles in the later stages of lipoprotein assembly remain unclear. Using N-acetyl-Leu-Leu-norleucinal
Guo-Zhou Zhi et al.
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 22(4), 335-337 (2002-10-23)
KR-100 is a newly developed long-lasting insecticide that incorporates cinerins substance, drug-release control substance and synergistic agent following certain procedures under carefully regulated conditions. Tests of the efficacy, toxicity, stability and long-term effect of KR-100 were conducted, and it was
N Fucci
The American journal of forensic medicine and pathology, 17(3), 231-232 (1996-09-01)
A case of acute intoxication of both methaqualone and diphenhydramine is reported. The analysis of these compounds was performed by liquid-liquid extraction (Toxi-Lab DPC procedure) followed by gas chromatography/mass spectrometry determination; both substances are contained in the pharmaceutical formulation called
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