700159P

Hyocholic acid

Avanti Research^™ - A Croda Brand

• Synonym(s): 3α,6α,7α-trihydroxy-5β-cholanic acid
• Empirical Formula (Hill Notation): C₂₄H₄₀ O₅
• CAS Number: 547-75-1
• Molecular Weight: 408.57
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 5 mg (700159P-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• lipid type: bile acids
• shipped in: dry ice
• storage temp.: −20°C
• InChI: 1S/C24H40O5/c1-13(4-7-19(26)27)15-5-6-16-20-17(9-11-23(15,16)2)24(3)10-8-14(25)12-18(24)21(28)22(20)29/h13-18,20-22,25,28-29H,4-12H2,1-3H3,(H,26,27)/t13-,14-,15-,16+,17+,18+,20+,21-,22+,23-,24-/m1/s1
• InChI key: DKPMWHFRUGMUKF-KWXDGCAGSA-N

Description

General description

Hyocholic acid, also called the 3α,6α,7α-trihydroxy-5β-cholanoic acid, is synthesized by the 6α-hydroxylation of chenodeoxycholic acid. It is a primary trihydroxylated bile acid associated with pigs. It is a minor bile acid in humans. Hyocholic acid is also synthesized from α-muricholic acid (MCA) in liver by the action of cytochrome P450 3A4 (CYP3A4).

Biochem/physiol Actions

Hyocholic acid levels are elevated in plasma and urine samples of patients with cholestatic liver disease and in hepatic cirrhosis.

Packaging

5 mL Amber Glass Screw Cap Vial (700159P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable