700094P
Avanti
cholestanol-d5
Avanti Research™ - A Croda Brand
Synonym(s):
111020
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C27H43D5O
CAS Number:
Molecular Weight:
393.70
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
description
2,2,3,4,4-pentadeuterio-5α-cholestan-3β-ol
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700094P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
Cholestanol-d5 is a deuterated form of cholestanol. Cholestanol is a plant saturated sterol and has Δ5 double bond to the 5α position in the cholesterol structure and is a 5α-dihydro derivative of cholesterol.
Biochem/physiol Actions
Cholestanol deuterated has been administered in small intestine samples for the quantification of sterols by gas chromatography-mass spectrometry. The levels of cholesterol and cholestanol are elevated in tendons and brain in cerebrotendinous xanthomatosis due to the CYP27A1 (Cytochrome P450 Family 27 Subfamily A Member 1) deficiency. Cholestanol-d5 is useful as an internal standard to spike sediment samples for tandem mass spectrometry (MS/MS) for fecal sterol quantification. Cholestanol is a cholesterol absorption biomarker.
Packaging
5 mL Amber Glass Screw Cap Vial (700094P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Microbial water quality and sedimentary faecal sterols as markers of sewage contamination in Kuwait.
B P Lyons et al.
Marine pollution bulletin, 100(2), 689-698 (2015-08-01)
Microbial water quality and concentrations of faecal sterols in sediment have been used to assess the degree of sewage contamination in Kuwait's marine environment. A review of microbial (faecal coliform, faecal streptococci and Escherichia coli) water quality data identified temporal
Ann Båvner et al.
Journal of lipid research, 51(9), 2722-2730 (2010-06-01)
The rare disease cerebrotendinous xanthomatosis (CTX) is due to a lack of sterol 27-hydroxylase (CYP27A1) and is characterized by cholestanol-containing xanthomas in brain and tendons. Mice with the same defect do not develop xanthomas. The driving force in the development
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service