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181104C

Avanti

Liver Extract Total

Avanti Research™ - A Croda Brand

Synonym(s):

Liver Total Lipid Extract (Bovine)

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About This Item

CAS Number:
86088-91-7
MDL number:
MFCD00037705
UNSPSC Code:
12352211
NACRES:
NA.25

form

chloroform solution

packaging

pkg of 1 × 4 mL (181104C-100mg)
pkg of 5 × 4 mL (181104C-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

25 mg/mL (181104C-100mg)
25 mg/mL (181104C-500mg)

lipid type

lipid extracts

shipped in

dry ice

storage temp.

−20°C

General description

Total Lipid Extract is a chloroform:methanol extract of the respective tissue (Brain, Soybean, Heart, etc.). This extract is partitioned against deionized water, and the chloroform phase is concentrated.

Application

Liver extract total has been used for the identification of cholesterol as an endogenous ligand of human macrophage-inducible C-type lectin (hMincle).

Packaging

5 mL Clear Glass Sealed Ampule (181104C-100mg)
5 mL Clear Glass Sealed Ampule (181104C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk_germany

WGK 3

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Human Mincle binds to cholesterol crystals and triggers innate immune responses
Kiyotake R, et al.
The Journal of biological chemistry, 290(42), 25322-25332 (2015)
Filip Duša et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183115-183115 (2019-11-11)
The cell membrane is mainly composed of lipid bilayers with inserted proteins and carbohydrates. Lipid bilayers made of purified or synthetic lipids are widely used for estimating the effect of target compounds on cell membranes. However, the composition of such
Ryoko Kiyotake et al.
The Journal of biological chemistry, 290(42), 25322-25332 (2015-08-25)
C-type lectin receptors (CLRs) are an emerging family of pattern recognition receptors that recognizes pathogens or damaged tissue to trigger innate immune responses. However, endogenous ligands for CLRs are not fully understood. In this study, we sought to identify an
Giuseppe Paglia et al.
Nature protocols, 12(4), 797-813 (2017-03-17)
Metabolomics and lipidomics aim to profile the wide range of metabolites and lipids that are present in biological samples. Recently, ion mobility spectrometry (IMS) has been used to support metabolomics and lipidomics applications to facilitate the separation and the identification

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