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Key Documents

H28807

Sigma-Aldrich

1-(2-Hydroxyethyl)piperazine

98%

Synonym(s):

2-Piperazinoethanol, Piperazine-1-ethanol

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About This Item

Empirical Formula (Hill Notation):
C6H14N2O
CAS Number:
Molecular Weight:
130.19
Beilstein/REAXYS Number:
104361
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

98%

refractive index

n20/D 1.506 (lit.)

bp

246 °C (lit.)

density

1.061 g/mL at 25 °C (lit.)

SMILES string

OCCN1CCNCC1

InChI

1S/C6H14N2O/c9-6-5-8-3-1-7-2-4-8/h7,9H,1-6H2

InChI key

WFCSWCVEJLETKA-UHFFFAOYSA-N

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pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

275.0 °F

flash_point_c

135 °C

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Ana I Loureiro et al.
Xenobiotica; the fate of foreign compounds in biological systems, 45(9), 828-839 (2015-04-29)
1. This study explores the impact of permeability and P-glycoprotein (P-gp) efflux, upon brain exposure to etamicastat, a new dopamine-β-hydroxylase (DBH) inhibitor and consequently brain levels of catecholamines. 2. Brain exposure to etamicastat (10 mg/kg), following intravenous administration to mice, was
Katalin F Medzihradszky et al.
Analytical chemistry, 87(5), 3064-3071 (2015-02-06)
Beam-type collision-induced dissociation (CID) data of intact glycopeptides isolated from mouse liver tissue are presented to illustrate characteristic fragmentation of differentially sialylated glycopeptides. Eight glycoforms of an O-linked glycopeptide from Nucleobindin-1 are distinguished on the basis of the precursor masses
Masahito Wakita et al.
Toxicon : official journal of the International Society on Toxinology, 103, 12-18 (2015-05-12)
The present study utilised a 'synaptic bouton' preparation of mechanically isolated rat hippocampal CA3 pyramidal neurons, which permits direct physiological and pharmacological quantitative analyses at the excitatory and inhibitory single synapse level. Evoked excitatory and inhibitory postsynaptic currents (eEPSCs and
Patrice N Mimche et al.
Hepatology (Baltimore, Md.), 62(3), 900-914 (2015-03-19)
Beyond the well-defined role of the Eph (erythropoietin-producing hepatocellular) receptor tyrosine kinases in developmental processes, cell motility, cell trafficking/adhesion, and cancer, nothing is known about their involvement in liver pathologies. During blood-stage rodent malaria infection we have found that EphB2
Yang Zhang et al.
PloS one, 10(6), e0128555-e0128555 (2015-06-05)
It has been well established that the architecture of chromatin in cell nuclei is not random but functionally correlated. Chromatin damage caused by ionizing radiation raises complex repair machineries. This is accompanied by local chromatin rearrangements and structural changes which

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