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CF0035

Benzimidazolyltetrafluoroethanesulfonyl fluoride

Name: Benzimidazolyltetrafluoroethanesulfonyl fluoride
Brand: ALDRICH

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About This Item

Linear Formula:

C₉H₅F₅O₂N₂S

MDL number:

MFCD32063418

UNSPSC Code:

12352101

form

solid

reaction suitability

reaction type: C-C Bond Formation

Application

Benzimidazolyltetrafluoroethanesulfonyl fluoride serves as a moderately reactive benzimidazolyltetrafluoroethanesulfonylation reagent. Fluoroalkylsulfonylation of the amine nitrogen greatly lowers the pKa value of the N-H and can be used to modulate the behaviour of the drug candidate or build additional molecular complexity around the highly acidic fluoroalkylsulfonamide nitrogen.

Automate your fluorination reactions with Synple Automated Synthesis Platform (SYNPLE-SC002)

Other Notes

Technology Spotlight: Fluoroalkylation: Expansion of Togni Reagents

Legal Information

Product of CF Plus Chemicals.

pictograms

GHS05

signalword

Danger

hcodes

H314

pcodes

P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338 + P310

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Articles

Fluoroalkylation: Expansion of Togni Reagents

The fluoroalkylation toolbox now includes Togni reagents, hypervalent iodine perfluoroalkylation reagents, fluoroalkyl bromides, silanes, carboxylates, and sulfonyl fluorides for late stage fluoroalkylation.