A77997

2-Aminopyridine

99%

• Synonym(s): 2-AP, 2-Pyridinamine, 2-Pyridylamine
• Empirical Formula (Hill Notation): C₅H₆N₂
• CAS Number: 504-29-0
• Molecular Weight: 94.11
• Beilstein/REAXYS Number: 105785
• EC Number: 207-988-4
• MDL number: MFCD00006312
• UNSPSC Code: 12352100
• PubChem Substance ID: 24891283
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 99%
• form: crystals
• bp: 204-210 °C (lit.)
• mp: 54-58 °C (lit.)
• SMILES string: Nc1ccccn1
• InChI: 1S/C5H6N2/c6-5-3-1-2-4-7-5/h1-4H,(H2,6,7)
• InChI key: ICSNLGPSRYBMBD-UHFFFAOYSA-N

Description

Application

2-Aminopyridine has been used as a reactant in the synthesis of 2-(2-aminopyridinium)acetyl starch with antioxidant property.
It can also be used:

• As a reactant in the synthesis of 3-aroylimidazopyridines from chalcones by aerobic oxidative amidation using copper acetate catalyst.
• In the synthesis of crystalline Cu(II) complex, di-μ-(2-aminopyridine(N,N′))-bis[(2,6 pyridinedicarboxylate)aquacopper(II)] tetrahydrate using 2,6-pyridinedicarboxylic acid and Cu(CH₃COO)₂.H₂O.
• As an imprinting molecule for the preparation of poly(methacrylic acid–ethylene glycol dimethacrylate) polymer. It is packed in micro-column for selective solid phase extraction of 2-aminopyridine.
• As a reactant in the synthesis of 2-aryl-3-(pyridin-2-yl)-1,3-thiazolidin-4-ones in the presence of Lewis acid catalysts.

Safety Information

• pictograms: GHS06,GHS05
• signalword: Danger
• hcodes: H301 + H311,H314,H412
• pcodes: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 197.6 °F - closed cup
• flash_point_c: 92 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges