934550

Silyl-ether based ROMP monomer

iPrSi

• Synonym(s): 2,2-Bis(1-methylethyl)-1,3-dioxa-2-silacyclohept-5-ene
• Empirical Formula (Hill Notation): C₁₁H₂₂O₂Si
• CAS Number: 2396521-63-2
• Molecular Weight: 214.38
• MDL number: MFCD34470659
• UNSPSC Code: 12162002
• NACRES: NA.21

Properties

• assay: ≥98%
• Quality Level: 100
• form: liquid
• composition: iPrSi
• color: colorless to pale yellow
• storage temp.: 2-8°C
• SMILES string: CC(C)[Si]1(C(C)C)OC/C=C\CCO1
• InChI: 1S/C11H22O2Si/c1-10(2)14(11(3)4)12-8-6-5-7-9-13-14/h5-6,10-11H,7-9H2,1-4H3/b6-5-
• InChI key: YBYQYMPJHKPHMH-WAYWQWQTSA-N

Description

General description

Ring opening metathesis polymerization (ROMP) monomers are attractive building block for advanced polymeric materials in the biomedical field. 2,2-Bis(1-methylethyl)-1,3-dioxa-2-silacyclohept-5-ene , or the silyl ether based ROMP monomer iPrSi, is a bifunctional cyclic olefin that can be used to synthesize a variety of marcomolecules and polymers with diverse compositions and complex structures. iPrSi can copolymerize with a variety of norbornene derivatives including small molecules and macromolecules, enabling the formation of backbone-degradable copolymers that can be used in a variety of biomedical applications. The ROMP polymerization method is superior as it permits the tailorability of the resulting polymer material.

Application

Synthesis of advanced polymeric materials for biomedical applications including:

• drug delivery
• molecular imaging
• self assembly
• hydrogels
• medical device coatings
• stimuli responsive material

Features and Benefits

• Copolymerize efficiency with a wide variety of norbornene-based (macro)monomers
• Controlled ROMP polymerization
• Silyl ether substitute can be tuned to control degradation

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable