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900542

Sigma-Aldrich

(2S)-2-Phenyl-3,4-dihydro-2H-pyrimido[2,1-b][1,3]benzothiazole

95%

Synonym(s):

Birman (S)-HBTM Resolution Catalyst

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About This Item

Empirical Formula (Hill Notation):
C16H14N2S
CAS Number:
Molecular Weight:
266.36
UNSPSC Code:
12161600
NACRES:
NA.22

Quality Level

assay

95%

form

powder or chunks

mp

125 °C

functional group

phenyl
thioether

storage temp.

2-8°C

SMILES string

C12=CC=CC=C1SC3=N[C@H](C4=CC=CC=C4)CCN23

Application

Organocatalyst for the kinetic resolution of secondary alcohols by acylation with anhydrides.

Related product

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Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Ximin Li et al.
The Journal of organic chemistry, 77(4), 1722-1737 (2012-01-31)
Kinetic resolution of racemic alcohols has been traditionally achieved via enzymatic enantioselective esterification and ester hydrolysis. However, there has long been considerable interest in devising nonenzymatic alternative methods for this transformation. Amidine-based catalysts (ABCs), a new class of enantioselective acyl

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