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Iron(III) chloride solution

greener alternative

0.2 M in 2-methyltetrahydrofuran

Ferric chloride solution
Linear Formula:
CAS Number:
Molecular Weight:
MDL number:
PubChem Substance ID:

Quality Level



reaction suitability

core: iron
reagent type: catalyst

greener alternative product characteristics

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.


0.2 M in 2-methyltetrahydrofuran

refractive index

n20/D 1.414


0.868 g/mL at 25 °C

greener alternative category


SMILES string




InChI key


General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. FeCl3 is used in many biomass conversion processes because of its unique properties such as nontoxicity, low-cost, abundance, and high selectivity. Here, this product is 0.2 M in 2-methyltetrahydrofuran and thus aligns with "Safer Solvents and Auxiliaries", "Use of Renewable Feedstocks", and has been enhanced for catalytic efficiency. Click here for more information.


Iron(III) chloride in greener solvent, 2-methyltetrahydrofuran (2-MeTHF) can be used:
  • As a mild oxidant for phenolic coupling reaction.
  • In dimerizing aryllithiumsand ketone enolates.
  • As a mild Lewis acid catalyst to catalyzes ene reactions.
  • In Nazarov cyclizations, Michael additions, and acetonation reactions.

2-Methyltetrahydrofuran (2-MeTHF): A Biomass-Derived Solvent with Broad Application in Organic Chemistry


50 mL in Sure/Seal™

Signal Word


Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Met. Corr. 1 - Skin Irrit. 2

Supplementary Hazards

Storage Class Code

3 - Flammable liquids



Flash Point(F)

14.0 °F - closed cup

Flash Point(C)

-10.0 °C - closed cup

Certificate of Analysis

Certificate of Origin

More documents

Quotes and Ordering

Abdelwareth A O Sarhan et al.
Chemical Society reviews, 38(9), 2730-2744 (2009-08-20)
In this critical review, the use of iron(III) chloride in oxidative C-C couplings of arenes and related unsaturated compounds is presented and reviewed. The approach allows highly selective dimerisations of phenol derivatives, naphthols, and heterocyclic compounds. Sequential couplings give access
Chen-Yu Chen et al.
Clinica chimica acta; international journal of clinical chemistry, 438, 337-341 (2014-10-05)
Insulin-like growth factor binding protein-1 (IGFBP-1) constitutes a subgroup of the insulin-like growth factor binding protein systems, and its concentration in amniotic fluid is 100-1000 times higher than the concentration in other body fluids. The aim of this study was
Xiaoqing Li et al.
The Journal of organic chemistry, 78(18), 9499-9504 (2013-08-28)
Halosulfonylation of terminal alkynes was achieved with sulfonylhydrazides as the sulfonyl precursor and inexpensive iron halide as halide source in the presence of TBHP, allowing the regio- and stereoselective generation of (E)-β-chloro and bromo vinylsulfones.
M Golder et al.
Thrombosis and haemostasis, 109(1), 53-60 (2012-11-28)
Factor VIII (FVIII), a procoagulant cofactor, plays a crucial role in the intrinsic coagulation cascade. A causal association between elevated FVIII levels and venous thrombosis incidence has been established; no such association has been confirmed with arterial thrombosis. The independent
D C Florian Wieland et al.
Colloids and surfaces. B, Biointerfaces, 109, 74-81 (2013-04-27)
The early stages of the formation of inorganic aggregates, composed of iron compounds at the solution-air interface, were investigated in situ. The properties of the solution-air interface were changed by using different Langmuir layers. In order to get insight into

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