689629

2-Amino-4-bromophenol

≥98.0% (HPLC)

• Synonym(s): 4-Bromo-2-aminophenol, NSC 523846
• Empirical Formula (Hill Notation): C₆H₆BrNO
• CAS Number: 40925-68-6
• Molecular Weight: 188.02
• Beilstein/REAXYS Number: 3236448
• MDL number: MFCD00235171
• UNSPSC Code: 12352100
• PubChem Substance ID: 329761279

Properties

• assay: ≥98.0% (HPLC)
• form: lumps
• mp: 130-135 °C
• SMILES string: Nc1cc(Br)ccc1O
• InChI: 1S/C6H6BrNO/c7-4-1-2-6(9)5(8)3-4/h1-3,9H,8H2
• InChI key: JHRIPENGTGSNPJ-UHFFFAOYSA-N

Description

Application

Reactant for:

• Preparation of (aryl)oxadiazolobenzoxazinones via Suzuki-Miyaura reaction
• Copper-catalyzed oxidative amination of benzoxazoles and related azoles via C-H and C-N bond activation
• Synthesis of N-(alkoxyphenyl)-aminocarbonylbenzoic acid derivatives as protein tyrosine phophatase 1B inhibitors
• Preparation of lipophilic deoxy-xylulose-phosphate reductoisomerase inhibitors
• Synthesis of benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase

Safety Information

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H315,H317,H319,H334,H335
• pcodes: P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves