64046

2,3-Dimercapto-1-propanol

≥98% (iodometric)

• Synonym(s): BAL, British anti-Lewisite, DMP, Dimercaprol, Dithioglycerol
• Linear Formula: HOCH₂CH(SH)CH₂SH
• CAS Number: 59-52-9
• Molecular Weight: 124.23
• Beilstein: 1732058
• EC Number: 200-433-7
• MDL number: MFCD00004864
• PubChem Substance ID: 57651969
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: ≥98% (iodometric)
• refractive index: n20/D 1.572-1.574; n20/D 1.573 (lit.)
• bp: 120 °C/15 mmHg (lit.)
• density: 1.239 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: OCC(S)CS
• InChI: 1S/C3H8OS2/c4-1-3(6)2-5/h3-6H,1-2H2
• InChI key: WQABCVAJNWAXTE-UHFFFAOYSA-N

Description

Application

2,3-Dimercapto-1-propanol has been used in synthesizing novel (2-substituted phenyl-1,3-dithiolan-4-yl) methanol (PDTM) derivatives, which are potent tyrosinase inhibitors. It can also be considered for developing new drugs against AIDS due to its ability to inhibit HIV-1 tat activity.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301 - H315 - H319 - H335
• Precautionary Statements: P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): 233.6 °F - closed cup
• Flash Point(C): 112 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves