630918

2-Bromo-N-methylaniline

95%

• Linear Formula: BrC₆H₄NHCH₃
• CAS Number: 6832-87-7
• Molecular Weight: 186.05
• MDL number: MFCD06798064
• UNSPSC Code: 12352100
• PubChem Substance ID: 24882362
• NACRES: NA.22

Properties

• assay: 95%
• refractive index: n20/D 1.6070 (lit.)
• bp: 107-109 °C/12 mmHg (lit.)
• density: 1.589 g/mL at 25 °C (lit.)
• functional group: amine; bromo
• SMILES string: CNc1ccccc1Br
• InChI: 1S/C7H8BrN/c1-9-7-5-3-2-4-6(7)8/h2-5,9H,1H3
• InChI key: SMVIAQFTVWDWDS-UHFFFAOYSA-N

Description

General description

2-Bromo-N-methylaniline can be synthesized via the reduction of 2-bromoformylanilide.

Application

2-Bromo-N-methylaniline can be used to synthesize benzimidazole derivatives, via one pot N-arylation of amides/cyclic amides in the presence of copper iodide nanoparticles. It can also be used in the synthesis of alkyltelluro-substituted aromatic amines, which can show radical trapping ability.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: 217.4 °F - closed cup
• flash_point_c: 103 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter