MilliporeSigma
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467804

Sigma-Aldrich

Hydroxylamine solution

50 wt. % in H2O, 99.999%

Synonym(s):
HDA
Linear Formula:
NH2OH
CAS Number:
Molecular Weight:
33.03
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

99.999%

concentration

50 wt. % in H2O

bp

107 °C

density

1.078 g/mL at 25 °C

SMILES string

NO

InChI

1S/H3NO/c1-2/h2H,1H2

InChI key

AVXURJPOCDRRFD-UHFFFAOYSA-N

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Application

Hydroxylamine solution (NH2OH) can be used as a reactant for the preparation of:
  • Primary amides from aldehydes catalyzed by an arene–ruthenium(II) complex.
  • Hydroxyaminoguanidines and carboxamide derivatives of ofloxacin for biological studies.
  • Fe3O4/Au (GoldMag) nanoparticles for antibody immobilization.

Reactant for preparation of:
  • Prodrug for cardiovascular agent Nω-hydroxy-L-arginine (NOHA, nitric oxide precursor)
  • Hydroxyaminoguanidines as anti-cancer agents
  • Nonsteroidal 2,3-dihydroquinoline glucocorticoid receptor agonists with reduced phosphoenolpyruvate caboxykinase (PEPCK) transactivation
  • Carboxamide derivatives of ofloxacin with improved antimicrobial properties
  • Analogues of coumarin based TNF-α converting enzyme (TACE) inhibitors
  • HIV integrase inhibitors

Packaging

10, 50 mL in poly bottle

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Desen. Expl. 4 - Eye Dam. 1 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3

Target Organs

Blood, Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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