331074

(4R)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane

96%

• Synonym(s): 2-[(4R)-2,2-Dimethyl-1,3-dioxolan-4-yl]ethanol
• Empirical Formula (Hill Notation): C₇H₁₄O₃
• CAS Number: 70005-89-9
• Molecular Weight: 146.18
• MDL number: MFCD02682966
• UNSPSC Code: 12352005
• PubChem Substance ID: 24859931
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 96%
• form: liquid
• refractive index: n20/D 1.4390 (lit.)
• bp: 207 °C (lit.)
• density: 1.045 g/mL at 25 °C (lit.)
• functional group: ether; hydroxyl; ketal
• SMILES string: CC1(C)OC[C@@H](CCO)O1
• InChI: 1S/C7H14O3/c1-7(2)9-5-6(10-7)3-4-8/h6,8H,3-5H2,1-2H3/t6-/m1/s1
• InChI key: YYEZYENJAMOWHW-ZCFIWIBFSA-N

Description

Application

(4R)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane can be used:

• To introduce a chiral center selectively in the carbon chain C10 during the total synthesis of protectin D1.
• As a starting material in the total synthesis of an anti-diabetic molecule cytopiloyne.
• As a starting material in the preparation of 4-¹⁵N-amino-2-butane-1,2-diol, which is used to synthesize ¹⁵N-labeled oligodeoxynucleotides.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 222.8 °F - closed cup
• flash_point_c: 106 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter