59539

(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol

≥97.0% (sum of enantiomers, GC)

• Synonym(s): (+)-2,3-O-Isopropylidene-L-threitol, (4S,5S)-4,5-Bis(hydroxymethyl)-2,2-dimethyl-1,3-dioxolane
• Empirical Formula (Hill Notation): C₇H₁₄O₄
• CAS Number: 50622-09-8
• Molecular Weight: 162.18
• Beilstein/REAXYS Number: 1280797
• EC Number: 256-658-6
• MDL number: MFCD00063761
• UNSPSC Code: 12352005
• PubChem Substance ID: 57651690
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥97.0% (sum of enantiomers, GC)
• form: solid
• optical activity: [α]20/D +3.0±0.5°, c = 5% in ethanol
• bp: 92-94 °C/0.1 mmHg (lit.)
• mp: 46-50 °C
• functional group: ether; hydroxyl; ketal
• SMILES string: CC1(C)O[C@@H](CO)[C@H](CO)O1
• InChI: 1S/C7H14O4/c1-7(2)10-5(3-8)6(4-9)11-7/h5-6,8-9H,3-4H2,1-2H3/t5-,6-/m0/s1
• InChI key: INVRLGIKFANLFP-WDSKDSINSA-N

Description

Application

(4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol can be used:

• As a key intermediate for the preparation of (6Z)-cis-9S,10R-epoxy-nonadecene, a female sex pheromone of elm spanworm.
• To prepare a chiral diphosphite ligand by reacting with phosphorochloridite using excess of NEt₃. 

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• ppe: Eyeshields, Gloves, type N95 (US)