306800

(R)-(+)-2-Chloropropionic acid

99%

• Linear Formula: CH₃CH(Cl)CO₂H
• CAS Number: 7474-05-7
• Molecular Weight: 108.52
• Beilstein/REAXYS Number: 1720258
• MDL number: MFCD00064204
• UNSPSC Code: 12352101
• PubChem Substance ID: 24858501
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 99%
• form: liquid
• optical activity: [α]20/D +14°, neat
• refractive index: n20/D 1.4345 (lit.)
• bp: 185-188 °C (lit.)
• density: 1.258 g/mL at 20 °C (lit.)
• functional group: carboxylic acid; chloro
• SMILES string: C[C@@H](Cl)C(O)=O
• InChI: 1S/C3H5ClO2/c1-2(4)3(5)6/h2H,1H3,(H,5,6)/t2-/m1/s1
• InChI key: GAWAYYRQGQZKCR-UWTATZPHSA-N

Description

Application

(R)-(+)-2-Chloropropionic acid can be used as a starting material in the synthesis of:       

• Thiolactic acid, a key intermediate, which is used for the preparation of 2(R),5(S)-oxathiolanones by reacting with pivalaldehyde.       
• (R)-2-chloropropionyl chloride, a key intermediate, which is utilized in the synthesis of (R)-4,5-dihydro-5-methylpyridazin-3(2H)-one derivative with pyrazolopyridine ring as a potential phosphodiesterase inhibitor.       
• 2-Chloropropionamide derivatives as protein disulfide isomerase (PID) inhibitors.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H314
• pcodes: P270 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1A
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 213.8 °F - closed cup
• flash_point_c: 101 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter