Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

249475

Sigma-Aldrich

4-(Trifluoromethyl)benzoyl chloride

97%

Synonym(s):

α,α,α-Trifluoro-p-toluoyl chloride

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CF3C6H4COCl
CAS Number:
Molecular Weight:
208.56
Beilstein/REAXYS Number:
391282
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

97%

form

liquid

refractive index

n20/D 1.476 (lit.)

bp

188-190 °C (lit.)
78-79 °C/16 mmHg (lit.)

density

1.404 g/mL at 25 °C (lit.)

functional group

acyl chloride

SMILES string

FC(F)(F)c1ccc(cc1)C(Cl)=O

InChI

1S/C8H4ClF3O/c9-7(13)5-1-3-6(4-2-5)8(10,11)12/h1-4H

InChI key

OXZYBOLWRXENKT-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

4-(Trifluoromethyl)benzoyl chloride undergoes microwave-promoted Suzuki-type coupling reaction with phenylboronic acid to yield 4-(trifluoromethyl)benzophenone.

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

172.4 °F - closed cup

flash_point_c

78 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Microwave-promoted cross-coupling of acid chlorides with arylboronic acids: a convenient method for preparing aromatic ketones.
Polackova V, et al.
Tetrahedron, 62(50), 11675-11678 (2006)
Risa Iima et al.
AAPS PharmSciTech, 19(6), 2679-2686 (2018-06-27)
We developed carriers of a 19F magnetic resonance imaging (19F MRI) agent, capable of responding to the temperature difference for cancer diagnosis. The carriers were based on high melting point (mp) neutral lipids, namely, tripalmitin (TPT) and tristearin (TSR) and

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service