180386
2,2,2-Trifluoroethylamine hydrochloride
98%
Synonym(s):
2-Amino-1,1,1-trifluoroethane hydrochloride
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All Photos(2)
About This Item
Linear Formula:
CF3CH2NH2 · HCl
CAS Number:
Molecular Weight:
135.52
Beilstein/REAXYS Number:
3652103
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
assay
98%
mp
220-222 °C (subl.) (lit.)
functional group
amine
fluoro
SMILES string
Cl.NCC(F)(F)F
InChI
1S/C2H4F3N.ClH/c3-2(4,5)1-6;/h1,6H2;1H
InChI key
ZTUJDPKOHPKRMO-UHFFFAOYSA-N
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Application
2,2,2-Trifluoroethylamine hydrochloride was used in the derivatization of aqueous carboxylic acids to the corresponding 2,2,2-trifluoroethylamide derivative.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Quincy LaRon Ford et al.
Journal of chromatography. A, 1145(1-2), 241-245 (2007-02-20)
We report a technique for the rapid, room temperature derivatization of aqueous carboxylic acids to the corresponding 2,2,2-trifluoroethylamide derivative. 3-Ethyl-1-[3-(dimethylamino)propyl]carbodiimide hydrochloride (EDC) and 2,2,2-trifluoroethylamine hydrochloride (TFEA) were added to aqueous samples of several acids of interest in environmental analytical chemistry
Yoshikazu Hattori et al.
Journal of biomolecular NMR, 68(4), 271-279 (2017-08-02)
The preparation of stable isotope-labeled proteins is important for NMR studies, however, it is often hampered in the case of eukaryotic proteins which are not readily expressed in Escherichia coli. Such proteins are often conveniently investigated following post-expression chemical isotope
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