166952
2-Hydroxybenzyl alcohol
99%
Synonym(s):
Salicyl alcohol, Saligenin
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About This Item
Linear Formula:
HOC6H4CH2OH
CAS Number:
Molecular Weight:
124.14
Beilstein/REAXYS Number:
1907195
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
assay
99%
form
solid
mp
83-85 °C (lit.)
solubility
ethanol: soluble 5%, clear to very slightly hazy, colorless to light yellow
functional group
hydroxyl
SMILES string
OCc1ccccc1O
InChI
1S/C7H8O2/c8-5-6-3-1-2-4-7(6)9/h1-4,8-9H,5H2
InChI key
CQRYARSYNCAZFO-UHFFFAOYSA-N
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General description
2-Hydroxybenzyl alcohol participates in the selective ring opening reaction of 4H-1,3,2-benzodioxasilines.
2-Hydroxybenzyl alcohol can be used as a coupling reagent to synthesize O-heterocycles.
2-Hydroxybenzyl alcohol can be used as a coupling reagent to synthesize O-heterocycles.
Application
2-Hydroxybenzyl alcohol was used in gastrodin production via biotransformation by cultured cells of Aspergillus foetidus and Penicillium cyclopium.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Selective ring opening of 4H-1, 3, 2-benzodioxasiline twin monomers.
Kempe P, et al.
New. J. Chem., 35(12), 2735-2739 (2011)
Linlin Fan et al.
Applied biochemistry and biotechnology, 170(1), 138-148 (2013-03-14)
The objective of this work was to take advantage of the resting cells of suitable fungus as an in vitro model to prepare gastrodin from p-2-hydroxybenzyl alcohol (HBA), which mainly exists in the metabolites of the plant Gastrodia elata Blume.
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Journal of controlled release : official journal of the Controlled Release Society, 113(3), 216-225 (2006-06-27)
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Journal of controlled release : official journal of the Controlled Release Society, 114(3), 369-380 (2006-08-15)
In this work, Electronic Speckle Pattern Interferometry (ESPI) is presented as a non-invasive tool to study drug transport in controlled release systems. ESPI is shown to be a feasible tool to measure drug film permeability via comparison with an ordinary
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The Journal of biological chemistry, 283(28), 19219-19228 (2008-05-17)
Salicyl alcohol oxidase is an extracellular enzyme that occurs in glandular reservoirs of chrysomelid leaf beetle larvae and catalyzes the formation of salicylaldehyde, a volatile deterrent used by the larvae against predators. Salicyl alcohol is the hydrolysis product of salicin
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