推薦產品
product name
Nα-甲苯磺酰基- L -赖氨酸氯甲基酮 盐酸盐, ≥96% (TLC), powder
生物源
synthetic (organic)
品質等級
化驗
≥96% (TLC)
形狀
powder
效力
10-100 μM effective concentration
溶解度
H2O: 50 mg/mL
儲存溫度
−20°C
SMILES 字串
Cl[H].Cc1ccc(cc1)S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl
InChI
1S/C14H21ClN2O3S.ClH/c1-11-5-7-12(8-6-11)21(19,20)17-13(14(18)10-15)4-2-3-9-16;/h5-8,13,17H,2-4,9-10,16H2,1H3;1H/t13-;/m0./s1
InChI 密鑰
YFCUZWYIPBUQBD-ZOWNYOTGSA-N
基因資訊
human ... NFKB1(4790) , NFKB2(4791)
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應用
Nα-对甲苯磺酰-L-赖氨酸氯甲基酮盐酸盐已用于：
- 在胰凝乳蛋白酶纯化中抑制粗提液中的胰蛋白酶，从而防止其与亲和载体结合
- 作为组织和细胞匀浆的蛋白酶抑制剂
- 作为胰蛋白酶抑制剂测定特定蛋白酶的活性水平
生化／生理作用
Nα-对甲苯磺酰-L-赖氨酸氯甲基酮盐酸盐(TLCK)抑制脂多糖(LPS)或细胞因子诱导的核因子κB (NF-κB)活化，从而抑制诱导型一氧化氮合酶(iNOS)和环氧合酶(COX-2)的转录激活。它可抑制所有有丝分裂原诱导的pp70s6k激活。还可通过抑制某些细胞株中和刺激下发生的胱天蛋白酶过程而抑制细胞株凋亡。
包裝
无底玻璃瓶。内含物在插入的融合锥内。
注意
20°C 干燥条件下储存时至少可稳定两年。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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