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Merck
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重要文件

SML2132

Sigma-Aldrich

巴西木素

同義詞:

苏枋精, (+)-Brazilin, 7,11b-二氢苯并[b]茚并[1,2-d]吡喃-3,6a,9,10(6H)-四醇, NSC 56652, (6aS,11bR)-7,11b-二氢-苯并[b]茚并[1,2-d]吡喃-3,6a,9,10(6H)-四醇, 6,6a,7,11b-四氢-3,6a,9,10-四羟基茚并[2,1-c]色烯, 天然红24

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About This Item

經驗公式(希爾表示法):
C16H14O5
CAS號碼:
分子量::
286.28
顏色索引編號:
75280
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77

光學活性

[α]/D 108.0 to 133.0°, c = 0.5 in methanol

顏色

white to very dark brown

溶解度

DMSO: 2 mg/mL

儲存溫度

2-8°C

SMILES 字串

O1C[C@]2([C@@H](c4c1cc(cc4)O)c3c(cc(c(c3)O)O)C2)O

InChI

1S/C16H14O5/c17-9-1-2-10-14(4-9)21-7-16(20)6-8-3-12(18)13(19)5-11(8)15(10)16/h1-5,15,17-20H,6-7H2/t15-,16+/m0/s1

InChI 密鑰

UWHUTZOCTZJUKC-JKSUJKDBSA-N

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生化/生理作用

巴西木素是一种天然的异黄酮类红色素,具有许多生物学活性,包括神经保护、抗炎、抗菌、抗增殖和抗氧化特性。人们认为其某些活性是由于其对转录因子NF-ΚB的调节.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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Zhan-Yuan Li et al.
Inflammation, 40(4), 1365-1374 (2017-05-13)
Hyperglycemia and inflammation play important roles in the pathogenesis of diabetic nephropathy (DN). Brazilin might be an effective pharmacological agent against hyperglycemia and inflammation. In our present study, we explored whether brazilin mitigated pathological progression, inflammation, and extracellular matrix (ECM)
Yanyan Jia et al.
International journal of molecular medicine, 38(1), 210-216 (2016-06-02)
Renal ischemia-reperfusion (I/R) injury is associated with high morbidity and mortality as there is currently no available effective therapeutic strategy with which to treat this injury. Thus, the aim of this study was to investigate the potential protective effects of
Eun Byeol Lee et al.
Archives of pharmacal research, 40(7), 825-835 (2017-07-02)
This study contributes to the continual discovery of lifespan-extending compounds from plants, using the Caenorhabditis elegans model system. An ethyl acetate soluble fraction of methanol extract from the heartwood of Caesalpinia sappan showed a significant lifespan-extending activity. Subsequent activity-guided chromatography

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