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A4256

Sigma-Aldrich

熊果苷

≥98% (HPLC)

同義詞:

4-羟基苯基-β- D -吡喃葡萄糖苷, p -熊果苷, 对苯二酚 β- D -吡喃葡萄糖苷

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About This Item

經驗公式（希爾表示法）:
C12H16O7
CAS號碼:
497-76-7
分子量：:
272.25
Beilstein:
89673
EC號碼:
207-850-3
MDL號碼:
MFCD00016915
分類程式碼代碼:
12352201
PubChem物質ID:
24890841
NACRES:
NA.25

生物源

synthetic or plant

品質等級

200

化驗

≥98% (HPLC)

形狀

powder

光學活性

[α]25/D -66.0 to -62.0 °, c = 3% (w/v) in water

技術

HPLC: suitable

顏色

light yellow

mp

195 °C

溶解度

water: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

儲存溫度

room temp

SMILES 字串

OC[C@H]1O[C@@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1

InChI 密鑰

BJRNKVDFDLYUGJ-RMPHRYRLSA-N

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相關類別

應用

熊果苷是一种糖基化的对苯二酚，用于黑色素生物合成的研究，并作为抑制剂来鉴定、区分和表征酪氨酸酶。

生化／生理作用

熊果苷是传统中药（TCM）中使用的糖基化对苯二酚。 熊果苷由于其酪氨酸酶抑制活性而抑制黑色素的形成。

其他說明

为了全面了解我们针对客户研究提供的各种单糖产品，建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析證明 (COA)

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Sang Mi An et al.
Phytotherapy research : PTR, 24(8), 1175-1180 (2010-01-16)
Tyrosinase (TYR) catalyzes rate-limiting steps of melanogenesis and thus its inhibitors are potentially useful as hypopigmenting agents. Recently, p-coumaric acid (p-CA) has been suggested to interfere with the pro-melanogenic actions of tyrosine due to its structural similarity with tyrosine (An
Hyo-Jong Lee et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 61(8), 817-825 (2012-04-11)
Arbutin, which is found in the genus Arctostaphylos, is an anti-oxidant and a depigmenting agent. The present study was designed to validate the anti-inflammatory effect of arbutin. The anti-inflammatory properties of arbutin were studied using a lipopolysaccharide (LPS)-stimulated murine BV2
Mi Jeong Kang et al.
Archives of pharmacal research, 34(4), 687-693 (2011-05-06)
A possible role of metabolism by intestinal bacteria in arbutin-induced toxicity was investigated in mammalian cell cultures. Following an incubation of arbutin with intestinal bacteria, either Bifidobacterium longum HY81 or Bifidobacterium adolescentis, for 24 h, its aglycone hydroquinone could be
Shinji Sakuma et al.
Molecular pharmaceutics, 9(4), 922-929 (2012-02-23)
A carboxyl group-terminated polyamidoamine dendrimer (generation: 3.0) bearing arbutin, which is a substrate of Na⁺/glucose cotransporter 1 (SGLT1), via a nonbiodegradable ω-amino triethylene glycol linker (PAMAM-ARB), inhibits SGLT1-mediated D-glucose uptake, as does phloridzin, which is a typical SGLT1 inhibitor. Here
Chunqiao Liu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 925, 104-109 (2013-04-02)
α-Arbutin is a glycosylated hydroquinone which has inhibitory function against tyrosinase. In this work, a one-step isolation of α-arbutin from Xanthomonas CGMCC 1243 fermentation broth by macroporous resin adsorption chromatography was investigated. The research results indicated that S-8 resin offered
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